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The benefits of migration, highlighted in Huntington's disease

Is HD a developmental disease? HD stops neurons migrating in developing brain, but maybe we can get them going again
February 10, 2017
New roles for huntingtin: removing a healthy protein to understand its function

Completely removing normal huntingtin in adults may disrupt healthy brain function, a recent study suggests.
September 26, 2017
Switch off the genome editor when you’re done

CRISPR genome editing just got an off-switch. We cut through the hype to explore the technology in HD
November 02, 2017
Success! ASO drug reduces levels of mutant protein in Huntington's disease patients

Amazing news from Ionis and Roche! HTTRx drug successfully lowers harmful huntingtin protein in spinal fluid
December 11, 2017
Exciting new Huntingtin lowering tool described

Exciting new Huntingtin Lowering work from @SangamoTx and @CHDIfoundation using "Zinc Fingers" to shut down expression of the mutant Huntingtin gene. More details on this exciting new technique here.
August 05, 2019
Start here!

Huntington's disease research news. In plain language. Written by scientists. For the global HD community.
May 22, 2023
Could halting CAG expansions be a new treatment for HD?

The gene MSH3 is getting a lot of attention in HD research lately. New findings suggest MSH3 lowering could halt CAG repeat expansions, offering a new therapeutic avenue.
October 05, 2023
Are there genetic connections between neurodegenerative diseases?

Genetic evidence suggests connections between a polyQ disease and ALS (Lou Gehrig’s disease). Why should HD people ca
December 01, 2010
The genetic 'gray area' of Huntington's disease: what does it all mean?

Intermediate alleles and reduced penetrance – the genetic 'gray area' of Huntington’s disease, explained
April 22, 2011
Gene therapy meets stem cells in liver disease success

Scientists combine gene therapy and stem cells to correct a genetic liver disease. Could this combo be retooled for H
December 26, 2011
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