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First Dolly, now Piglet; a new Huntington’s disease pig knock-in model confirmed

First Dolly, now Piglet; a new Huntington’s disease pig knock-in model confirmed

For the first time in HD research, an animal model has been created in pigs using 2 cutting edge DNA editing t

Caroline CaseyJuly 10, 2018

HDBuzz Enrolls in Enroll-HD

HDBuzz Enrolls in Enroll-HD

As promised, HDBuzz's Jeff Carroll finally signed up for the Enroll-HD study. Learn more about this important global HD "observational study" here.

Dr Jeff CarrollJuly 31, 2018

Disappointing news from LEGATO-HD trial of laquinimod in Huntington's disease

Disappointing news from LEGATO-HD trial of laquinimod in Huntington's disease

The LEGATO-HD trial of laquinimod did not slow progression of Huntington's disease. Here's the lowdown.

Dr Jeff CarrollAugust 02, 2018

Roche announces details of its 'pivotal' huntingtin-lowering study

Roche announces details of its 'pivotal' huntingtin-lowering study

The GENERATION-HD1 trial will test whether RG6042 – formerly Ionis-HTTRx – slows the progression of Huntington's disease

Dr Jeff CarrollSeptember 17, 2018

Kids sometimes get Huntington’s disease too

Kids sometimes get Huntington’s disease too

Finally, a big study that shows what childhood HD looks like. This will help us work out if new drugs work in children too

Dr Michael FlowerOctober 10, 2018

Advances on many fronts in the battle against the protein that causes Huntington's disease

Advances on many fronts in the battle against the protein that causes Huntington's disease

This fall sees exciting announcements from a number of companies focused on novel Huntingtin Lowering technologies, including Wave, PTC and Voyager

Dr Jeff CarrollDecember 04, 2018

Huntington's disease therapeutics conference 2019 - Day 1

Huntington's disease therapeutics conference 2019 - Day 1

HDBuzz reports from the annual Huntington’s disease therapeutics conference in Palm Springs

Joel StantonFebruary 27, 2019

Huntington's disease therapeutics conference 2019 - Day 2

Huntington's disease therapeutics conference 2019 - Day 2

New tools to bridge the gap between the lab and patients in our update from day 2 of the 2019 HD Therapeutics conference

Joel Stanton and Dr Jeff CarrollFebruary 28, 2019

Huntington's disease therapeutics conference 2019 - Day 3

Huntington's disease therapeutics conference 2019 - Day 3

New insights into the huntingtin protein, and further progress in turning genetic quirks that modify the course of HD into treatments, on the final day of the therapeutics conference

Joel Stanton and Dr Jeff CarrollMarch 05, 2019

An Updated Trial Design for Roche's Huntingtin Lowering Trial

An Updated Trial Design for Roche's Huntingtin Lowering Trial

Roche announces an update to the GENERATION HD1 trial after reviewing the ASO open label extension study

Dr Jeff CarrollMarch 21, 2019

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