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Update confirms Huntington's disease 'gene silencing' trial on track
Ionis says its trial of HTTRx, intended to lower huntingtin protein, is fully recruited and plans to extend it
October 15, 2017
Switch off the genome editor when you’re done
CRISPR genome editing just got an off-switch. We cut through the hype to explore the technology in HD
November 02, 2017
Success! ASO drug reduces levels of mutant protein in Huntington's disease patients
Amazing news from Ionis and Roche! HTTRx drug successfully lowers harmful huntingtin protein in spinal fluid
December 11, 2017
New interest in an old target
Promising results in mice provide renewed optimism for mGluR5 antagonists
January 30, 2018
Huntington's disease therapeutics conference 2018 - day 2
DNA takes centre stage for day 2 of the Huntington's Disease Therapeutics Conference in Palm Springs
March 01, 2018
Huntington's disease therapeutics conference 2018 - day 3
Updates from day 3 of the Huntington’s Disease Therapeutics Conference: huntingtin protein - and lowering it
March 02, 2018
HDSA’s Q&A on the latest huntingtin-lowering update from Ionis and Roche
Our friends at @hdsa have produced this really good Q&A document about the latest huntingtin-lowering news.
April 26, 2018
First Dolly, now Piglet; a new Huntington’s disease pig knock-in model confirmed
For the first time in HD research, an animal model has been created in pigs using 2 cutting edge DNA editing t
July 10, 2018
Disappointing news from LEGATO-HD trial of laquinimod in Huntington's disease
The LEGATO-HD trial of laquinimod did not slow progression of Huntington's disease. Here's the lowdown.
August 02, 2018
Roche announces details of its 'pivotal' huntingtin-lowering study
The GENERATION-HD1 trial will test whether RG6042 – formerly Ionis-HTTRx – slows the progression of Huntington's disease
September 17, 2018
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