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What Pigs Revealed that Mice Missed in Huntington’s Disease
9 min read
Latest News
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Huntexil update: EMA asks for further trial
2 min read
European Medicines Agency (EMA) tells NeuroSearch a European license for Huntexil in HD requires another large trial
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KMO inhibitor drug improves lifespan of Huntington's disease mice
8 min read
Positive results from tests of a new 'KMO inhibiting' drug in Huntington's disease mice
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Meet the enemy: neutron ray reveals HD protein structure
5 min read
Scientists use beams of neutrons to study the structure of clumps of mutant huntingtin protein
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'Floating' gene-silencing drugs into the brain with exosomes
6 min read
Exosomes – tiny bubbles made by cells – could be used to get gene silencing drugs from the bloodstream into the brain
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Improving Huntington's disease clinical trial recruitment through patient and family education
5 min read
How can we improve recruitment into Huntington's disease clinical trials? Talking directly with families works!
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Chubby mice reveal the importance of the hypothalamus in Huntington's disease
6 min read
Huntington's disease mice are fat but HD patients lose weight – is a brain area called the hypothalamus to blame?
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The genetic 'gray area' of Huntington's disease: what does it all mean?
8 min read
Intermediate alleles and reduced penetrance – the genetic 'gray area' of Huntington’s disease, explained
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Dimebon fails in late-stage human HD clinical trial
3 min read
Dimebon fails to improve symptoms in HD patients in the HORIZON trial
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FDA: further trial needed for Huntexil approval in HD
2 min read
Bad news for Huntexil – the FDA requires another trial before it can be approved in the US
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Successful gene therapy trial in Parkinson’s Disease gives hope for HD
5 min read
Success for brain ‘gene therapy’ in Parkinson’s disease – good news for similar treatments being developed in HD
HDBuzz Trial Tracker
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Updates from the ongoing Phase 3 INVEST-HD trial of votoplam
Updates from the Phase 1b/2a REGEN4HD trial of neural stem cell therapy hNSC-01
Updates from the ongoing Phase 2/3 FALCON-HD trial of SKY-0515
