Latest News
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Sealing the gap: a case for slower, smarter DNA repair
⏱️ 7 min read | Your body assembles DNA like a team of workers who set and bond a pattern of tiles. A recent study shows that one special assistant might slow somatic CAG expansion and delaying HD onset.
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Minocycline: the end of the road?
DOMINO clinical trial result: minocycline doesn’t slow down HD and shouldn’t be studied in larger trials.
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TRACK-HD reveals significant changes in pre-symptomatic HD mutation carriers and patients
The one-year report from the TRACK-HD study demonstrates a number of changes in pre-symptomatic HD-mutation carriers
HDBuzz Trial Tracker
Sites for Phase 3 trial for votoplam, INVEST-HD, now open. Updates on recruitment and first dosing imminent.
Novartis/PTC Therapeutics
Expected:
Spring 2026
REGEN4HD, Phase 1 stem cell implantation study commences
University of California, Irvine
Expected:
Not disclosed
Progress update for NCT06585449 – A Study to Evaluate ALN-HTT02
Alnylam Pharmaceuticals
Expected:
2026
Updates from the ongoing placebo-controlled Phase 2/3 FALCON-HD trial
Skyhawk Therapeutics
Expected:
Not disclosed
Previously featured
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Sealing the gap: a case for slower, smarter DNA repair
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HDBuzz 2025 Annual Report: Here’s what you made possible
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Skyhawk reports encouraging 12-month results for oral Huntington’s disease drug SKY-0515
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May 2026: This Month in Huntington’s Disease Research
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Fixing the Recipe: Lowering a Slice of Huntingtin
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