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Huntington’s disease research news.

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  • Can’t Get You Out of My Head: The Huntington’s Disease Symptom That’s More Than Just Repetition

    Can’t Get You Out of My Head: The Huntington’s Disease Symptom That’s More Than Just Repetition

    5 min read

Latest News

  • AMT-130 at Four Years: Hopeful Signs, Complex Controls

    AMT-130 at Four Years: Hopeful Signs, Complex Controls

    12 min read

    uniQure reports that after 4 years, people given high-dose AMT-130 continue to show signs of slower HD progression, providing hope for their recent regulatory submission. But the new analyses are nuanced. We unpack the hopeful, but complex results.

HDBuzz Trial Tracker

Initial Phase 1 clinical data from ALN-HTT02

Alnylam Pharmaceuticals
Expected: Q4 2026

Phase 3 trial of SOM3355 expected to begin

SOM Biotech
Expected: Q4 2026

Regulatory updates on AMT-130 following US and UK submissions

uniQure
Expected: Not disclosed
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Update on plans for a Phase 2/3 study of WVE-003

Wave Life Sciences
Expected: Not disclosed

PRECISE-HD Phase 3 trial of pridopidine begins recruitment

Prilenia-Ferrer
Expected: N/A

Updates from the ongoing Phase 3 INVEST-HD trial of votoplam

Novartis/PTC Therapeutics
Expected: Not disclosed

Updates from the Phase 1b/2a REGEN4HD trial of neural stem cell therapy hNSC-01

University of California, Irvine
Expected: Not disclosed

Further update from the Phase 1/2a trial of VO659

Vico Therapeutics
Expected: Not disclosed

Updates from the Phase 1/2 trial of RG6662 (SPK-10001) gene therapy

Roche
Expected: Not disclosed

Updates from the ongoing Phase 2/3 FALCON-HD trial of SKY-0515

Skyhawk Therapeutics
Expected: Not disclosed

Updates from the Phase 1 INSIGHTT trial of SRP-1005

Sarepta Therapeutics
Expected: Not disclosed

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