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AMT-130 at Four Years: Hopeful Signs, Complex Controls
12 min read
Latest News
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September 2026: This month in Huntington’s disease research
5 min read
September brought progress across the HD research landscape. From brain waves and visual thinking to DNA repeats, nutrition, inclusive care, new technologies, and encouraging SKY-0515 data, we round up a busy month in Huntington’s disease research.
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New collaboration seeks to speed Huntington's disease drug licensing
6 min read
Critical Path Institute launches new initiative to get HD drugs licensed as quickly as possible
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HDSA’s Q&A on the latest huntingtin-lowering update from Ionis and Roche
5 min read
Our friends at @hdsa have produced this really good Q&A document about the latest huntingtin-lowering news.
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Exciting Experiments in "Open Science" by Huntington's Researchers
5 min read
Brave scientists open their notebooks to help drive HD research at the risk of getting "scooped".
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The structure of the protein that causes Huntington's disease, revealed
5 min read
Huntingtin protein's structure is now clear thanks to cryo-electron microscopy. This is kind of a big deal
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Huntington's disease therapeutics conference 2018 – day 3
14 min read
Updates from day 3 of the Huntington’s Disease Therapeutics Conference: huntingtin protein – and lowering it
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Huntington's disease therapeutics conference 2018 – day 2
4 min read
DNA takes centre stage for day 2 of the Huntington's Disease Therapeutics Conference in Palm Springs
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Huntington's disease therapeutics conference 2018 – day 1
7 min read
Our daily roundup of the science presented at the 2018 HD Therapeutics Conference in Palm Springs
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An early role for the Huntington's disease gene – but don't believe all the headlines
13 min read
A surprising new paper sheds light on the role of the HD gene early in development. Should we worry?
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New interest in an old target
5 min read
Promising results in mice provide renewed optimism for mGluR5 antagonists
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Ask the expert: Q&A on the huntingtin-lowering trial program
14 min read
In a Q&A coordinated by the UK HD Association, Dr Ed Wild answers questions on the recently-announced trial
HDBuzz Trial Tracker
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Updates from the ongoing Phase 3 INVEST-HD trial of votoplam
Updates from the Phase 1b/2a REGEN4HD trial of neural stem cell therapy hNSC-01
Updates from the ongoing Phase 2/3 FALCON-HD trial of SKY-0515
