Latest News
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AMT-130 at Four Years: Hopeful Signs, Complex Controls
12 min read
uniQure reports that after 4 years, people given high-dose AMT-130 continue to show signs of slower HD progression, providing hope for their recent regulatory submission. But the new analyses are nuanced. We unpack the hopeful, but complex results.
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Huntington's disease therapeutics conference 2019 – Day 3
12 min read
New insights into the huntingtin protein, and further progress in turning genetic quirks that modify the course of HD into treatments, on the final day of the therapeutics conference
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Huntington's disease therapeutics conference 2019 – Day 2
5 min read
New tools to bridge the gap between the lab and patients in our update from day 2 of the 2019 HD Therapeutics conference
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Huntington's disease therapeutics conference 2019 – Day 1
9 min read
HDBuzz reports from the annual Huntington’s disease therapeutics conference in Palm Springs
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HDSA FAQ on the Roche/Genentech RG6042 program
18 min read
HDSA's frequently asked questions factsheet about the huntingtin-lowering trial ASO program was so good we stole it (with permission)
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Kids sometimes get Huntington’s disease too
6 min read
Finally, a big study that shows what childhood HD looks like. This will help us work out if new drugs work in children too
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Roche announces details of its 'pivotal' huntingtin-lowering study
10 min read
The GENERATION-HD1 trial will test whether RG6042 – formerly Ionis-HTTRx – slows the progression of Huntington's disease
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Disappointing news from LEGATO-HD trial of laquinimod in Huntington's disease
5 min read
The LEGATO-HD trial of laquinimod did not slow progression of Huntington's disease. Here's the lowdown.
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HDBuzz Enrolls in Enroll-HD
12 min read
As promised, HDBuzz's Jeff Carroll finally signed up for the Enroll-HD study. Learn more about this important global HD "observational study" here.


