Latest News
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Through a Broader Lens: Looking at Non-Motor Symptoms in HD
Sleep deficits precede motor problems in HD
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Looking Past the Spin: Results from a Clinical Trial of Cysteamine
Phase 2/3 clinical trial results prove inconclusive for Huntington's drug cysteamine.
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A recycled drug gives us new insight in to HD
An existing drug could give a boost to HD brain cells – but it may need more testing before it’s back in the clinic
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Through the eyes of a friend: changes in mood and behavior in early HD
Companions of HD gene carriers are more likely to notice psychological changes in presymptomatic HD.
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A multiple sclerosis drug that works for Huntington's disease: the real deal or too good to be true?
Fingolimod, a drug used in multiple sclerosis, prevents memory problems in HD mice. Would it work in patients?
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Mapping the anatomy of HD: a whole-brain history
A new book for researchers describes a century of HD anatomy and presents evidence that HD affects the whole brain.
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Liftoff: First humans treated with gene silencing drugs for HD!
Major Announcement: First HD patients treated with gene silencing drugs
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HDBuzz primer: Clinical trial designs and phases
HDBuzz untangles hope from hype in clinical trial announcements
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A Few Bad Seeds: Using Brain Fluid to Grow Clumps in Brain Cells
HD brain fluid makes brain cells grow clumps.
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New tool to measure outcomes in Huntington’s Disease clinical trials
A better tool for HD trials! New research shows innovative way to measure mutant Huntingtin outside the brain
HDBuzz Trial Tracker
Progress update for NCT06585449 – A Study to Evaluate ALN-HTT02
Additional insights from Phase 2 study results and update on plans for Phase 3 trial for votoplam
Updates from the ongoing placebo-controlled Phase 2/3 FALCON-HD trial
Previously featured
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Putting it in print: oral drug branaplam lowered huntingtin, but safety concerns halted development
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A hitch in the stitch reveals why DNA sequence patterns matter in Huntington’s disease
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Worms to the Rescue: Separating the Good, the Bad, and the Clumpy Huntingtin
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January 2026: This Month in Huntington’s Disease Research
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Phase 1 results announced for Skyhawk’s drug SKY-0515
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