HDBuzz – Page 29 – Huntington’s disease research news.

Huntington’s disease research news.

In plain language. Written by scientists.
For the global HD community.

UniQure Secures Type A Meeting with FDA: What This Means for AMT-130

January 12, 2026

Latest News

Putting Huntington’s disease medications to the test: results from the Neuro-HD trial

⏱️6 min read | A clinical trial, Neuro-HD, compared 3 common drugs for HD symptoms. The 1 year study found no “best” medication, but clear differences between treatments. The results support a personalised, symptom-by-symptom approach to HD treatment.

January 8, 2026

Planting trees together: The 2016 Huntington's Disease Society of America Convention

HDBuzz summarizes the science from an unusually large and energized @HDSA convention in Baltimore

June 13, 2016
Huntingtin takes a trip: harmful proteins pass between brain cells

Harmful misfolded huntingtin can travel between brain cells via messenger particles called exosomes

June 6, 2016
Important drug targets yielded by new genetic study of HD

A genetic study confirms that minute differences in DNA repair genes can influence the age of HD symptom onset.

May 2, 2016
Thinking clearly about the earliest symptoms of HD and which brain regions control them

HD reaches more brain structures than we thought: new research broadens our understanding of the earliest signs of HD

April 18, 2016
How NOT to write a news article about a clinical trial

A confusing story about a huntingtin lowering trial is published in the Telegraph, but cool new stuff is happening!

March 10, 2016
Huntington's Disease Therapeutics Conference 2016 – day 3

Stem cells and modeling Huntington's disease in our final Therapeutics Conference report

February 28, 2016
Huntington's Disease Therapeutics Conference 2016 – day 2

Strategies for getting rid of mutant huntingtin & clinical trial updates: day 2 of the HD therapeutics conference

February 25, 2016
Huntington's Disease Therapeutics Conference 2016 – day 1

Proteins and DNA – Jeff and Ed report from day 1 of the 2016 #huntingtonsdisease therapeutics conference

February 24, 2016
Harnessing the power of viruses to treat Huntington's disease

Researchers design a virus to more effectively deliver gene-silencing drugs throughout the brain.

February 1, 2016
Through a Broader Lens: Looking at Non-Motor Symptoms in HD

Sleep deficits precede motor problems in HD

January 25, 2016

HDBuzz Trial Tracker

Request Meeting with FDA to Define Next Steps for AMT-130

uniQure

Expected: Q1 2026

Topline data from SKY-0515’s Phase 1 Clinical Study

Skyhawk Therapeutics

Expected: Mid 2026

Phase 3 for SOM3355 to commence

SOM Biotech

Expected: Q4 2026

Progress update for NCT06585449 – A Study to Evaluate ALN-HTT02

Alnylam Pharmaceuticals

Expected: 2026

GENERATION-HD2 Trial Expected to Complete

Roche

Expected: 2026

Update on Planned Phase 2/3 Study for WVE-003

Wave Life Sciences

Expected: Not disclosed

Update on Phase 1/2a Clinical Data of VO659

Vico Therapeutics

Expected: Not disclosed

Additional insights from Phase 2 study results and update on plans for Phase 3 trial for votoplam

Novartis/PTC Therapeutics

Expected: Not disclosed

Previously featured

Putting Huntington’s disease medications to the test: results from the Neuro-HD trial

January 8, 2026
HDBuzz Is Officially Independent: What This Means, and Why It Matters

January 5, 2026
2025: Year in Review

December 29, 2025
Break Up With Your CAGs: How Three Letters Could Change Huntington’s Disease

December 22, 2025
First participants dosed in new POINT-HD huntingtin-lowering trial

December 18, 2025

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