'Floating' gene-silencing drugs into the brain with exosomes

'Floating' gene-silencing drugs into the brain with exosomes

Exosomes – tiny bubbles made by cells – could be used to get gene silencing drugs from the bloodstream into the brain

Dr Ed WildMay 19, 2011

Improving Huntington's disease clinical trial recruitment through patient and family education

Improving Huntington's disease clinical trial recruitment through patient and family education

How can we improve recruitment into Huntington's disease clinical trials? Talking directly with families works!

Dr Jeff CarrollMay 12, 2011

Chubby mice reveal the importance of the hypothalamus in Huntington's disease

Chubby mice reveal the importance of the hypothalamus in Huntington's disease

Huntington's disease mice are fat but HD patients lose weight – is a brain area called the hypothalamus to blame?

Dr Ed WildMay 02, 2011

The genetic 'gray area' of Huntington's disease: what does it all mean?

The genetic 'gray area' of Huntington's disease: what does it all mean?

Intermediate alleles and reduced penetrance – the genetic 'gray area' of Huntington’s disease, explained

Dr Nayana LahiriApril 22, 2011

Dimebon fails in late-stage human HD clinical trial

Dimebon fails in late-stage human HD clinical trial

Dimebon fails to improve symptoms in HD patients in the HORIZON trial

Dr Jeff CarrollApril 11, 2011

FDA: further trial needed for Huntexil approval in HD

FDA: further trial needed for Huntexil approval in HD

Bad news for Huntexil – the FDA requires another trial before it can be approved in the US

Dr Jeff CarrollApril 04, 2011

Successful gene therapy trial in Parkinson’s Disease gives hope for HD

Successful gene therapy trial in Parkinson’s Disease gives hope for HD

Success for brain ‘gene therapy’ in Parkinson’s disease – good news for similar treatments being developed in HD

Dr Jeff CarrollMarch 31, 2011

Gene silencing for HD: the story so far

Gene silencing for HD: the story so far

Is gene silencing as exciting as it sounds for HD, and what might the future hold?

Dr Ed WildMarch 22, 2011

Interview: Graeme Bilbe, Global Head for Neuroscience at Novartis

Interview: Graeme Bilbe, Global Head for Neuroscience at Novartis

HDBuzz interviews Graeme Bilbe, Global Head for Neuroscience at pharmaceutical giant Novartis, about their HD researc

Dr Ed WildMarch 14, 2011

What do sheep brains have to do with HD?

What do sheep brains have to do with HD?

How smart are sheep, and why do HD researchers care?

Dr Jeff CarrollMarch 09, 2011

Interview: CHDI Management

Interview: CHDI Management

HDBuzz interviews three top scientists from CHDI, the biggest funder and driver of HD research worldwide

Dr Jeff CarrollFebruary 25, 2011