New results bring BDNF therapies into focus

New results bring BDNF therapies into focus

Some unexpected findings suggest new ways to aim at an old target in HD

Dr Jeff CarrollAugust 18, 2014

2CARE study of coenzyme Q for Huntington's disease ends in disappointment

2CARE study of coenzyme Q for Huntington's disease ends in disappointment

The largest ever HD drug trial, testing coenzyme Q10, is halted for 'futility'. What does that mean for HD research?

Dr Jeff CarrollAugust 13, 2014

A starring role for astrocytes in Huntington's disease?

A starring role for astrocytes in Huntington's disease?

Brain cells called astrocytes might play a bigger role than previously thought in Huntington's disease

Terry Jo BichellJuly 29, 2014

HD mice provide a useful failure

HD mice provide a useful failure

Can drug trials that fail be helpful? A HD mouse study provides solid evidence of an approach that doesn't help HD

Dr Jeff CarrollJuly 22, 2014

Illuminating the progression of Huntington’s disease

Illuminating the progression of Huntington’s disease

Researchers have used mice with glowing brain cells to decipher the first steps of neurodegeneration

Dr Tamara MaiuriJune 25, 2014

Jumping genes: Huntington's disease protein invades brain transplants

Jumping genes: Huntington's disease protein invades brain transplants

A long-term study of the brains of HD patients who received grafts of fetal tissue reveals a surprising result

Dr Jeff CarrollMay 26, 2014

The brain in Huntington's disease: greater than the sum of its parts?

The brain in Huntington's disease: greater than the sum of its parts?

An important new study asks the question: what parts of the brain might need most help in HD?

Dr Jeff CarrollMay 19, 2014

NUB1: enhancing clearance to decrease mutant huntingtin

NUB1: enhancing clearance to decrease mutant huntingtin

NUB1 increases mutant huntingtin removal from cells, reducing the toxic effects of HD in fruit flies

Lakshini MendisMay 12, 2014

Could HD be caused by amino acid deficiency?

Could HD be caused by amino acid deficiency?

Does a specific amino acid deficiency contribute to the development of HD?

Dr Jeff CarrollApril 21, 2014

Raptor announces results of cysteamine trial for Huntington's disease

Raptor announces results of cysteamine trial for Huntington's disease

Raptor Pharmaceuticals announces intermediate results from a long-term study of cysteamine in Huntington's disease

Dr Jeff CarrollApril 10, 2014

Sleep, cilia and HD

Sleep, cilia and HD

New studies shed some light on the function of sleep in animals, with interesting implications for HD research

Graham EastonMarch 06, 2014

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