The brain in Huntington's disease: greater than the sum of its parts?

The brain in Huntington's disease: greater than the sum of its parts?

An important new study asks the question: what parts of the brain might need most help in HD?

Dr Jeff CarrollMay 19, 2014

NUB1: enhancing clearance to decrease mutant huntingtin

NUB1: enhancing clearance to decrease mutant huntingtin

NUB1 increases mutant huntingtin removal from cells, reducing the toxic effects of HD in fruit flies

Lakshini MendisMay 12, 2014

Could HD be caused by amino acid deficiency?

Could HD be caused by amino acid deficiency?

Does a specific amino acid deficiency contribute to the development of HD?

Dr Jeff CarrollApril 21, 2014

Raptor announces results of cysteamine trial for Huntington's disease

Raptor announces results of cysteamine trial for Huntington's disease

Raptor Pharmaceuticals announces intermediate results from a long-term study of cysteamine in Huntington's disease

Dr Jeff CarrollApril 10, 2014

Sleep, cilia and HD

Sleep, cilia and HD

New studies shed some light on the function of sleep in animals, with interesting implications for HD research

Graham EastonMarch 06, 2014

Huntington's Disease Therapeutics Conference 2014: day 3

Huntington's Disease Therapeutics Conference 2014: day 3

Biomarkers and preparing for trials: the third & final day of the 2014 Huntington's Disease Therapeutics Conference

Dr Ed WildFebruary 28, 2014

Huntington's Disease Therapeutics Conference 2014: day 2

Huntington's Disease Therapeutics Conference 2014: day 2

Cells, circuits and systems: day 2 of the 2014 HD Therapeutics conference

Dr Jeff CarrollFebruary 27, 2014

Huntington's Disease Therapeutics Conference 2014: day 1

Huntington's Disease Therapeutics Conference 2014: day 1

HDBuzz reports from the opening day of science sessions at the 2014 HD Therapeutics Conference in Palm Springs.

Dr Ed WildFebruary 26, 2014

Prana announces results of Reach2HD trial of PBT2 for Huntington's disease

Prana announces results of Reach2HD trial of PBT2 for Huntington's disease

Results are in for a clinical trial testing the drug PBT2 for HD. Are the claims in the announcement justified?

Dr Jeff CarrollFebruary 20, 2014

Does high-dose creatine "slow the onset" of Huntington's Disease?

Does high-dose creatine "slow the onset" of Huntington's Disease?

A new study claims that high-dose creatine "slows the onset of Huntington Disease". How much hope and how much hype?

Dr Jeff CarrollFebruary 11, 2014

Joint HDBuzz Prizewinner: Yeast studies suggest a new way to protect cells from 'oxidative damage'

Joint HDBuzz Prizewinner: Yeast studies suggest a new way to protect cells from 'oxidative damage'

Researchers identify Gpx1, a protein that may be protective in HD. An existing drug can mimic its antioxidant effect.

Leora FoxFebruary 05, 2014