New roles for huntingtin: removing a healthy protein to understand its function

New roles for huntingtin: removing a healthy protein to understand its function

Completely removing normal huntingtin in adults may disrupt healthy brain function, a recent study suggests.

Dr Leora FoxSeptember 26, 2017

Precision huntingtin-lowering drug trials target the mutant protein

Precision huntingtin-lowering drug trials target the mutant protein

WAVE Life Sciences launches PRECISION clinical trial to suppress the mutant Huntington's disease protein

Dr Michael FlowerAugust 25, 2017

A step forward for gene editing: CRISPR-Cas9 and HD

A step forward for gene editing: CRISPR-Cas9 and HD

Evolving CRISPR-Cas9 techniques can now be used to edit the HD gene in a living mouse brain.

Dr Leora FoxJuly 26, 2017

New study reveals a potential HD biomarker

New study reveals a potential HD biomarker

A potential HD biomarker has been uncovered in a recent clinical study

Dr Leora FoxJune 07, 2017

Has a "wonder drug" for dementia been discovered? (Spoiler alert: no.)

Has a "wonder drug" for dementia been discovered? (Spoiler alert: no.)

Media reports of a wonder drug for neurodegenerative diseases like Huntington's disease are overhyped

Dr Michael FlowerMay 07, 2017

Huntington's Disease Therapeutics Conference 2017 - Day 3

Huntington's Disease Therapeutics Conference 2017 - Day 3

HDBuzz summarises final day of the 2017 Huntington's Disease Therapeutics Conference in Malta

Professor Ed WildApril 30, 2017

Huntington's Disease Therapeutics Conference 2017 - Day 2

Huntington's Disease Therapeutics Conference 2017 - Day 2

HDBuzz summarises all the science from the 2017 Huntington's Disease Therapeutics Conference in Malta - day 2

Dr Jeff CarrollApril 29, 2017

Huntington's Disease Therapeutics Conference 2017 - Day 1

Huntington's Disease Therapeutics Conference 2017 - Day 1

HDBuzz summarises all the science from the 2017 Huntington's Disease Therapeutics Conference in Malta - day 1

Dr Jeff CarrollApril 27, 2017

Enemy at the gates – huntingtin disrupts nuclear transport

Enemy at the gates – huntingtin disrupts nuclear transport

Two recent studies show how a cellular border control system goes wrong in HD, opening new avenues for HD research.

Tom PeskettApril 21, 2017

FDA approves a new drug for symptoms of Huntington's disease

FDA approves a new drug for symptoms of Huntington's disease

Deutetrabenazine becomes the first new drug in a decade licensed by the FDA for symptoms of Huntington's disease

Dr Jeff CarrollApril 05, 2017

Sheep leading the flock: metabolism and biomarkers in HD

Sheep leading the flock: metabolism and biomarkers in HD

Sheep can help us to identify HD biomarkers and recognize metabolic changes that occur before symptoms develop.

Dr Leora FoxMarch 27, 2017

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