symptoms
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When a Short Fuse Becomes a Storm: Understanding Irritability in Huntingtonās Disease
For people living with HD, irritability can erupt like a storm, sudden and overwhelming. In a new study, researchers spoke directly to people with HD to understand what irritability truly feels like.
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One Disease, Many Paths: How Brain Wiring Shapes Huntingtonās Symptoms
HD starts with a single gene change, but its effects travel many roads. New work shows how brain networks breakdown or reroute. Whether movement, thinking, or mood are most affected, we may be able to guide care in a more personalized direction.
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Unlocking the Mindās Eye: How Huntingtonās Disease Changes How We See and Process the World
For many with Huntingtonās disease, recognising faces, navigating familiar places, or reading can be difficult. Scientists studied how and when HD affects how the brain processes what we seeācrucial research to improve support for people with HD.
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Stars in the Sky: Psychosis in Huntingtonās Disease
New research shines a light on an often-overlooked side of Huntingtonās diseaseāpsychosis. Understanding the impact of psychosis on daily life and progression of other HD symptoms could be key to providing better care and support.
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Brain Gym: Staying Mentally Active May Slow Huntingtonās Disease
New research suggests that cognitive engagement – keeping your brain busy with activities like reading, puzzles, or learning new skills – could help protect the brain, possibly slowing progression of symptoms of Huntingtonās disease.
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Decoding apathy in Huntingtonās disease: a new lens on motivation and decision-making
Apathy in Huntingtonās disease isnāt just a lack of motivationāitās a shift in how the brain weighs decisions. A new study sheds light on how targeted treatments could help restore motivation and improve quality of life.
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Interruptions are encouraged
A CRISPR-based approach called ābase editingā is being explored to develop a new potential treatment for Huntington's disease. Editing a single letter in the genetic code with base editing may be the key for delaying HD symptoms, maybe by a decade.
By Dr Chris Kay -
Drug to treat movement symptoms of HD approved by FDA
The FDA has approved valbenazine, also known as INGREZZA, as a treatment for the movement symptoms of Huntingtonās disease
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KINECT-HD trial shows valbenazine improves involuntary movements in Huntington's disease
In a much-needed bit of good news for the Huntington's disease community, Neurocrine Bioscience's KINECT-HD trial showed that treatment with valbenazine significantly reduced the involuntary movements called chorea
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HD Young Adult Study defines the sweet spot: symptom-free with measurable changes
We know that HD-related changes can occur many years before symptom onset, but how early do those changes begin? A team of researchers set out to determine that with a new comprehensive study in pre-manifest HD young adults.