symptoms
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Brain Gym: Staying Mentally Active May Slow Huntington’s Disease
5 min read
New research suggests that cognitive engagement – keeping your brain busy with activities like reading, puzzles, or learning new skills – could help protect the brain, possibly slowing progression of symptoms of Huntington’s disease.
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Decoding apathy in Huntington’s disease: a new lens on motivation and decision-making
7 min read
Apathy in Huntington’s disease isn’t just a lack of motivation—it’s a shift in how the brain weighs decisions. A new study sheds light on how targeted treatments could help restore motivation and improve quality of life.
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Interruptions are encouraged
6 min read
A CRISPR-based approach called “base editing” is being explored to develop a new potential treatment for Huntington's disease. Editing a single letter in the genetic code with base editing may be the key for delaying HD symptoms, maybe by a decade.
By Dr Chris Kay -
Drug to treat movement symptoms of HD approved by FDA
6 min read
The FDA has approved valbenazine, also known as INGREZZA, as a treatment for the movement symptoms of Huntington’s disease
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KINECT-HD trial shows valbenazine improves involuntary movements in Huntington's disease
7 min read
In a much-needed bit of good news for the Huntington's disease community, Neurocrine Bioscience's KINECT-HD trial showed that treatment with valbenazine significantly reduced the involuntary movements called chorea
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HD Young Adult Study defines the sweet spot: symptom-free with measurable changes
7 min read
We know that HD-related changes can occur many years before symptom onset, but how early do those changes begin? A team of researchers set out to determine that with a new comprehensive study in pre-manifest HD young adults.
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FDA approves a new drug for symptoms of Huntington's disease
4 min read
Deutetrabenazine becomes the first new drug in a decade licensed by the FDA for symptoms of Huntington's disease
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Sorry folks, the PRIDE-HD trial did NOT show that Pridopidine slows the progression of Huntington's disease
13 min read
HDBuzz helps untangle some bold claims about the just-announced results of the PRIDE-HD trial of pridopidine in HD
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Important drug targets yielded by new genetic study of HD
8 min read
A genetic study confirms that minute differences in DNA repair genes can influence the age of HD symptom onset.
By Dr Leora Fox -
Thinking clearly about the earliest symptoms of HD and which brain regions control them
8 min read
HD reaches more brain structures than we thought: new research broadens our understanding of the earliest signs of HD