mouse-model
-
Building a Better Mouse(trap): A New Model of Huntington’s Disease
New mouse model gives insights into Huntington's disease
-
Taking new targets to the bank: the DNA repair protein ‘ATM’ is overactive in Huntington's disease
HD causes the normally helpful protein "ATM" to get a little overzealous. Now we can look for drugs to settle it down
-
Drug Improves Huntington’s Symptoms in Mice – and Their Offspring
HD drug changes DNA folding across generations
-
mTORC1 tips the scales in Huntington’s disease mice
Weighing the scales on mTORC1: A possible new target for HD therapeutics?
-
New results bring BDNF therapies into focus
Some unexpected findings suggest new ways to aim at an old target in HD
-
HD mice provide a useful failure
Can drug trials that fail be helpful? A HD mouse study provides solid evidence of an approach that doesn't help HD
-
Illuminating the progression of Huntington’s disease
Researchers have used mice with glowing brain cells to decipher the first steps of neurodegeneration
-
Could HD be caused by amino acid deficiency?
Does a specific amino acid deficiency contribute to the development of HD?
-
Sleep, cilia and HD
New studies shed some light on the function of sleep in animals, with interesting implications for HD research
-
Calming down the immune system helps Huntington's disease mice
CB2-activating drug improves survival and symptoms in Huntington's disease mice through calming down the immune syste