mouse-model
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Novel research technique suggests an antioxidant gene protects vulnerable neurons
Researchers use a new technique in an HD mouse to uncover a gene, Gpx6, that is protective to vulnerable neurons.
By Dr Leora Fox -
Building a Better Mouse(trap): A New Model of Huntington’s Disease
New mouse model gives insights into Huntington's disease
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Taking new targets to the bank: the DNA repair protein ‘ATM’ is overactive in Huntington's disease
HD causes the normally helpful protein "ATM" to get a little overzealous. Now we can look for drugs to settle it down
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Drug Improves Huntington’s Symptoms in Mice – and Their Offspring
HD drug changes DNA folding across generations
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mTORC1 tips the scales in Huntington’s disease mice
Weighing the scales on mTORC1: A possible new target for HD therapeutics?
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New results bring BDNF therapies into focus
Some unexpected findings suggest new ways to aim at an old target in HD
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HD mice provide a useful failure
Can drug trials that fail be helpful? A HD mouse study provides solid evidence of an approach that doesn't help HD
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Illuminating the progression of Huntington’s disease
Researchers have used mice with glowing brain cells to decipher the first steps of neurodegeneration
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Could HD be caused by amino acid deficiency?
Does a specific amino acid deficiency contribute to the development of HD?
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Sleep, cilia and HD
New studies shed some light on the function of sleep in animals, with interesting implications for HD research