featured
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Steadying genetic stumble could help slow Huntington's disease
Using CRISPR technology, scientists uncovered genes that control C-A-G genetic stumbles in Huntington's disease
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Community voices power change through research surveys
HDYO released data from recent surveys of the global HD community. Learn more about the findings and how surveys can help shape the future of HD care and support.
By Dr Leora Fox -
Huntington’s Disease Clinical Expert Prof. Ed Wild Shares Hopeful View For 2025
The HDBuzz team caught up with editor emeritus and Huntington's disease specialist, Prof Ed Wild to hear his thoughts on what 2025 has in store for the Huntington's disease community
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New Insights Into Why Huntington’s Disease Has Delayed Onset
A highly-anticipated scientific paper has landed! This new work challenges current theories in Huntington’s disease research, uncovering how runaway CAG repeats erode cell identity in certain types of brain cells, leading to their death.
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Spotting HD Early: The Clues Hidden in Young Brains
Researchers have detected early changes in brain scans and biomarkers in young people with the Huntington’s disease gene, 20 years before symptoms are predicted to appear. These findings could help develop medicines to treat HD earlier in life.
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Replacing What Is Lost: Regrowing Damaged Brain Cells for Huntington’s Disease
Cell replacement therapy is making massive strides for other diseases. But what about Huntington’s disease? Can we use technological advancements in this area to replace lost brain cells with the hope of repairing and reversing disease?
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Decoding apathy in Huntington’s disease: a new lens on motivation and decision-making
Apathy in Huntington’s disease isn’t just a lack of motivation—it’s a shift in how the brain weighs decisions. A new study sheds light on how targeted treatments could help restore motivation and improve quality of life.
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2024: Year in Review
As we begin 2025, we look back on all of the Huntington’s disease research news and progress the field has made in the last 12 months.
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2024 HDBuzz Prize: A NEAT new dance partner for Huntingtin
We’re proud to announce AJ Keefe as our last HDBuzz Prize winner of 2024! Our cells are an intricate choreography between various molecular dancers. Knowing who moves well with whom, and how that changes with disease, could help advance drugs for HD.
By AJ Keefe -
Moving into the Fast Lane: uniQure and the FDA Are on the Same Track for Accelerated Approval
In an update shared today, uniQure announced alignment with the US drug regulator on key criteria for accelerated approval of drugs for Huntington’s disease.