Articles with the topic: featured

Drug to treat movement symptoms of HD approved by FDA

Drug to treat movement symptoms of HD approved by FDA

The FDA has approved valbenazine, also known as INGREZZA, as a treatment for the movement symptoms of Huntington’s disease

Dr Leora Fox and Dr Rachel HardingAugust 22, 2023

Youthful competitors: young brain cells oust the old

Youthful competitors: young brain cells oust the old

Replacing cells with HD in the brain could be an effective treatment strategy. Recent work shows that glia injected into mouse brains take over and oust the older cells, but for a surprising reason - because of age, not HD!

Dr Sarah HernandezAugust 08, 2023

Huntington’s disease therapeutics conference 2023 - Day 3

Huntington’s disease therapeutics conference 2023 - Day 3

Check out research updates from Day 3 of the 2022 HD Therapeutics Conference #HDTC2023

Joel Stanton, Dr Rachel Harding, Dr Leora Fox, and Dr Tamara MaiuriMay 22, 2023

Huntington’s disease therapeutics conference 2023 - Day 2

Huntington’s disease therapeutics conference 2023 - Day 2

Check out research updates from Day 2 of the 2022 HD Therapeutics Conference #HDTC2023

Joel Stanton, Dr Rachel Harding, Dr Leora Fox, and Dr Tamara MaiuriMay 04, 2023

Huntington’s disease therapeutics conference 2023 - Day 1

Huntington’s disease therapeutics conference 2023 - Day 1

Check out research updates from Day 1 of the 2022 HD Therapeutics Conference #HDTC2023

Joel Stanton, Dr Rachel Harding, Dr Leora Fox, and Dr Tamara MaiuriApril 26, 2023

PROOF-HD study of pridopidine ends with negative result

PROOF-HD study of pridopidine ends with negative result

The phase 3 trial missed its primary endpoint of slowing loss of function in Huntington’s disease

Professor Ed WildApril 25, 2023

Astrocytes: The new star in HD research?

Astrocytes: The new star in HD research?

A new article summarizes what the Huntington's disease field has found about a type of brain cell called an astrocyte. These star-shaped cells help keep brain cells healthy and could be leveraged for developing new HD therapeutics.

Dr Sarah HernandezApril 19, 2023

Hunting for balance: how the huntingtin protein compensates in HD

Hunting for balance: how the huntingtin protein compensates in HD

Researchers look at the cause and effect of various forms of the HTT protein. They find both expanded and unexpanded HTT contribute to brain cell communication and the brain has an amazing capacity to compensate for changes related to disease

Dr Sarah Hernandez and Dr Leora FoxApril 05, 2023

Roche Phase II GENERATION HD2 study underway

Roche Phase II GENERATION HD2 study underway

Roche released a community letter in early 2023, to share that their Phase II clinical trial to study the huntingtin-lowering drug, tominersen, is now underway. In this article, we summarise the latest news about this huntingtin-lowering drug.

Dr Rachel HardingFebruary 14, 2023

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