For Sleep Awareness Week (March 9-15), HDBuzz is giving a wake up call to sleep disturbances in Huntington’s disease. New research suggests sleep changes start early, before other symptoms appear—but there are steps you can take to catch better Z's!
New research suggests that cognitive engagement - keeping your brain busy with activities like reading, puzzles, or learning new skills - could help protect the brain, possibly slowing progression of symptoms of Huntington’s disease.
Like a movie editor removing bloopers, our cells also edit their protein machines to make films worth watching. New research finds the cell’s movie editor is distracted in Huntington’s disease.
A highly-anticipated scientific paper has landed! This new work challenges current theories in Huntington’s disease research, uncovering how runaway CAG repeats erode cell identity in certain types of brain cells, leading to their death.
Changes in thinking, learning, and memory are some of the most distressing and impactful in Huntington’s disease. Sage Therapeutics was advancing their drug dalzanemdor to treat these symptoms, but unfortunately this program will be halted.
The phase 3 trial missed its primary endpoint of slowing loss of function in Huntington’s disease
Read updates from clinical trials and scientific research on Huntington’s disease from Day 1 of the 2022 HDF Milton Wexler Biennial Symposium #HDF2022
HDBuzz is saddened to share the news that the VIBRANT-HD trial of the oral huntingtin-lowering drug, branaplam, has been temporarily suspended for the safety of participants.
Scientists use human fetal tissue to look at HD brain development. But what do developmental changes mean when symptoms don’t occur until decades after birth?