Huntington’s disease research news. In plain language. Written by scientists. For the global HD community.
Cannabis, or medical marijuana, has been touted as a treatment for lots of conditions, and Huntington’s disease is no exception. Whenever it hits the news there’s a lot of interest, and recently cannabis found the spotlight again with videos claiming it can reverse the nerve cell damage in Huntington’s disease. These are extraordinary assertions that deserve to be explored.
The National Institute for Health's Office for Research Integrity has ruled that Huntington's disease researcher Dr Paul Muchowski, formerly of the Gladstone Institutes at University of California San Francisco, committed "research misconduct by falsifying and fabricating data" in several applications for funding. What does this mean for Muchowski's published HD therapies research?
The immune system is thought to behave abnormally in Huntington's disease. Now, a drug that activates CB2 receptors on immune cells has been shown to improve symptoms and survival in HD mice - with interesting implications for the immune system as a target for HD therapies.