Scientists use human fetal tissue to look at HD brain development. But what do developmental changes mean when symptoms don’t occur until decades after birth?
Researchers show that highly expanded CAGs in the HD gene can cause early developmental changes using 3D brain models called organoids. What’d they find?
Hot off the presses - New publication gives more details about the results of Ionis and Roche's safety study with a Huntingtin-lowering ASO
Is HD a developmental disease? HD stops neurons migrating in developing brain, but maybe we can get them going again
A surprising new mouse study suggests the mutant HD gene may do some of its damage during embryonic development
A small study suggests kids with the HD mutation but no symptoms have subtle differences in growth. What does it mean