Researchers show that highly expanded CAGs in the HD gene can cause early developmental changes using 3D brain models called organoids. What’d they find?
Hot off the presses - New publication gives more details about the results of Ionis and Roche's safety study with a Huntingtin-lowering ASO
Is HD a developmental disease? HD stops neurons migrating in developing brain, but maybe we can get them going again
A surprising new mouse study suggests the mutant HD gene may do some of its damage during embryonic development
A small study suggests kids with the HD mutation but no symptoms have subtle differences in growth. What does it mean