Articles with the topic: metabolism

Screening the entire genome for new drug targets for HD

Screening the entire genome for new drug targets for HD

Scientists screen the ENTIRE genome to find new potential therapeutic targets for HD. This ambitious study provides a wealth of data for HD researchers

Dr Rachel HardingFebruary 23, 2020

Sheep leading the flock: metabolism and biomarkers in HD

Sheep leading the flock: metabolism and biomarkers in HD

Sheep can help us to identify HD biomarkers and recognize metabolic changes that occur before symptoms develop.

Dr Leora FoxMarch 27, 2017

Through a Broader Lens: Looking at Non-Motor Symptoms in HD

Through a Broader Lens: Looking at Non-Motor Symptoms in HD

Sleep deficits precede motor problems in HD

Melissa ChristiansonJanuary 25, 2016

mTORC1 tips the scales in Huntington’s disease mice

mTORC1 tips the scales in Huntington’s disease mice

Weighing the scales on mTORC1: A possible new target for HD therapeutics?

Joseph OchabaJanuary 27, 2015

Can this synthetic oil help feed the brain in Huntington's disease?

Can this synthetic oil help feed the brain in Huntington's disease?

A new study shows a synthetic oil called triheptanoin changes how HD brains use energy. But will it help HD?

Dr Jeff CarrollJanuary 15, 2015

Largest creatine clinical trial for Huntington's disease halted after 'futility' analysis

Largest creatine clinical trial for Huntington's disease halted after 'futility' analysis

CREST-E, a trial of the supplement creatine, has been stopped after an early analysis found it couldn't show benefit

Professor Ed WildOctober 29, 2014

2CARE study of coenzyme Q for Huntington's disease ends in disappointment

2CARE study of coenzyme Q for Huntington's disease ends in disappointment

The largest ever HD drug trial, testing coenzyme Q10, is halted for 'futility'. What does that mean for HD research?

Dr Jeff CarrollAugust 13, 2014

Does high-dose creatine "slow the onset" of Huntington's Disease?

Does high-dose creatine "slow the onset" of Huntington's Disease?

A new study claims that high-dose creatine "slows the onset of Huntington Disease". How much hope and how much hype?

Dr Jeff CarrollFebruary 11, 2014

The sweet lowdown: Huntington's disease brains use sugar differently

The sweet lowdown: Huntington's disease brains use sugar differently

New observations suggest that the brains of HD mutation carriers consume energy differently. Do we care? (Yes!)

Dr Jeff CarrollOctober 11, 2013