Articles with the topic: clinical-trial

Liftoff: First humans treated with gene silencing drugs for HD!

Major Announcement: First HD patients treated with gene silencing drugs

Dr Jeff Carroll | October 22, 2015

HDBuzz primer: Clinical trial designs and phases

HDBuzz untangles hope from hype in clinical trial announcements

Dr Jeff Carroll and Melissa Christianson | October 09, 2015

Measuring harmful huntingtin protein in the brain’s bath water

How will we know whether HD-lowering treatments are working? New advancements in the detection of mutant huntingtin.

Dr Michael Orth | May 18, 2015

2015 Huntington's Disease Therapeutics Conference: Day 2

Day 2 of updates from the annual HD Therapeutics Conference in Palm Springs

Dr Jeff Carroll | February 26, 2015

Can this synthetic oil help feed the brain in Huntington's disease?

A new study shows a synthetic oil called triheptanoin changes how HD brains use energy. But will it help HD?

Dr Jeff Carroll | January 15, 2015

Positive results announced for re-worked tetrabenazine drug in Huntington's disease

Modified 'heavy hydrogen' form of tetrabenazine appears safe and effective for chorea in Huntington's disease

Dr Jeff Carroll | December 22, 2014

Huntington's disease clinical trial announcement: huntingtin-lowering drug to enter Phase I trial in 2015

A clinical trial for an exciting therapy against HD is planned for 2015. The first step is to make sure it is safe.

Dr Leora Fox | November 04, 2014

Largest creatine clinical trial for Huntington's disease halted after 'futility' analysis

CREST-E, a trial of the supplement creatine, has been stopped after an early analysis found it couldn't show benefit

Professor Ed Wild | October 29, 2014

2CARE study of coenzyme Q for Huntington's disease ends in disappointment

The largest ever HD drug trial, testing coenzyme Q10, is halted for 'futility'. What does that mean for HD research?

Dr Jeff Carroll | August 13, 2014

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