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Taking new targets to the bank: the DNA repair protein ‘ATM’ is overactive in Huntington's disease

Taking new targets to the bank: the DNA repair protein ‘ATM’ is overactive in Huntington's disease

HD causes the normally helpful protein "ATM" to get a little overzealous. Now we can look for drugs to settle it down

Terry Jo BichellMarch 09, 2015

Lighting the way: A new biomarker for Huntington’s disease

Lighting the way: A new biomarker for Huntington’s disease

A new biomarker reveals brain changes in early Huntington's disease.

Melissa ChristiansonApril 20, 2015

Would ewe believe it? GM1, sheep and Huntington's disease

Would ewe believe it? GM1, sheep and Huntington's disease

HD researchers and sheep farmers are collaborating on a brain fat called GM1, but a clinical trial is a long way off

Dr Leora FoxJuly 28, 2015

Huge study reveals new 'genetic modifiers' of Huntington's disease

Huge study reveals new 'genetic modifiers' of Huntington's disease

GeM-HD identifies the first solid leads in the hunt for genetic variations that affect Huntington's disease onset

Dr Jeff CarrollJuly 31, 2015

New tool to measure outcomes in Huntington’s Disease clinical trials

New tool to measure outcomes in Huntington’s Disease clinical trials

A better tool for HD trials! New research shows innovative way to measure mutant Huntingtin outside the brain

Megan KrenchSeptember 03, 2015

HDBuzz primer: Clinical trial designs and phases

HDBuzz primer: Clinical trial designs and phases

HDBuzz untangles hope from hype in clinical trial announcements

Dr Jeff Carroll and Melissa ChristiansonOctober 09, 2015

Liftoff: First humans treated with gene silencing drugs for HD!

Liftoff: First humans treated with gene silencing drugs for HD!

Major Announcement: First HD patients treated with gene silencing drugs

Dr Jeff CarrollOctober 22, 2015

Mapping the anatomy of HD: a whole-brain history

Mapping the anatomy of HD: a whole-brain history

A new book for researchers describes a century of HD anatomy and presents evidence that HD affects the whole brain.

Dr Leora FoxNovember 04, 2015

A recycled drug gives us new insight in to HD

A recycled drug gives us new insight in to HD

An existing drug could give a boost to HD brain cells – but it may need more testing before it’s back in the clinic

Dr Leora FoxDecember 15, 2015

Looking Past the Spin: Results from a Clinical Trial of Cysteamine

Looking Past the Spin: Results from a Clinical Trial of Cysteamine

Phase 2/3 clinical trial results prove inconclusive for Huntington's drug cysteamine.

Melissa ChristiansonDecember 18, 2015

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