HDBuzz

Huntington’s disease research news.

In plain language. Written by scientists.
For the global HD community.

Change Language
HDBuzz
  • EHDN 2026 Part 1: What’s next in the Huntington’s disease treatment pipeline?

    EHDN 2026 Part 1: What’s next in the Huntington’s disease treatment pipeline?

    9 min read

Latest News

  • Skyhawk’s drug trial takes flight in the US

    Skyhawk’s drug trial takes flight in the US

    4 min read

    Skyhawk’s FALCON-HD trial has dosed the first participants in the US with the drug, SKY-0515. The once-daily pill targets two drivers of HD, but does it actually slow disease? That’s the big question this study hopes to answer.

HDBuzz Trial Tracker

Phase 3 trial of SOM3355 expected to begin

SOM Biotech
Expected: Q4 2026

FDA accepts BLA for Priority Review, with a target decision date of 1 May 2027.

uniQure
Expected: May 2027

Launch of pivotal clinical trial for brezosiran

Alnylam Pharmaceuticals
Expected: 2027
Show 8 more Show less

Update on plans for a Phase 2/3 study of WVE-003

Wave Life Sciences
Expected: Not disclosed

PRECISE-HD Phase 3 trial of pridopidine begins recruitment

Prilenia-Ferrer
Expected: N/A

Updates from the ongoing Phase 3 INVEST-HD trial of votoplam

Novartis/PTC Therapeutics
Expected: Not disclosed

Updates from the Phase 1b/2a REGEN4HD trial of neural stem cell therapy hNSC-01

University of California, Irvine
Expected: Not disclosed

Further update from the Phase 1/2a trial of VO659

Vico Therapeutics
Expected: Not disclosed

Updates from the Phase 1/2 trial of RG6662 (SPK-10001) gene therapy

Roche
Expected: Not disclosed

Updates from the ongoing Phase 2/3 FALCON-HD trial of SKY-0515

Skyhawk Therapeutics
Expected: Not disclosed

Updates from the Phase 1 INSIGHTT trial of SRP-1005

Sarepta Therapeutics
Expected: Not disclosed

Previously featured

More…

Start here

New to HD Research? Click here to get an overview

Follow HDBuzz

Sign up to our monthly email summary by entering your email address on our mailing list page.

Suggest an article

Is there something you want us to write about? Tell us about it here. We consider all suggestions but can’t promise to write content about any particular suggestion.

Email editors@hdbuzz.net