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  • Joining the Starting Lineup: MutLβ’s Role in DNA Repeat Expansions

    Joining the Starting Lineup: MutLβ’s Role in DNA Repeat Expansions

Latest News

HDBuzz Trial Tracker

Expected submission for regulatory approval of AMT-130 in the UK

uniQure
Expected: Q3 2026

Expected submission of BLA for regulatory approval of AMT-130 in the US

uniQure
Expected: Q3 2026

Sites for Phase 3 trial for votoplam, INVEST-HD, now open. Updates on recruitment and first dosing imminent.

Novartis/PTC Therapeutics
Expected: Spring 2026
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REGEN4HD, Phase 1 stem cell implantation study commences

University of California, Irvine
Expected: Not disclosed

Phase 3 for SOM3355 to commence

SOM Biotech
Expected: Q4 2026

Progress update for NCT06585449 – A Study to Evaluate ALN-HTT02

Alnylam Pharmaceuticals
Expected: 2026

Update on Planned Phase 2/3 Study for WVE-003

Wave Life Sciences
Expected: Not disclosed

Update on Phase 1/2a Clinical Data of VO659

Vico Therapeutics
Expected: Not disclosed

First participant in Phase 1/2 gene therapy trial dosed

Roche
Expected: Not disclosed

Updates on data leading to closing of GENERATION-HD2 trial

Roche
Expected: Not disclosed

Updates on data leading to closing of POINT-HD trial

Roche
Expected: Not disclosed

Updates from the ongoing placebo-controlled Phase 2/3 FALCON-HD trial

Skyhawk Therapeutics
Expected: Not disclosed

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