Latest News
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High-power brain scans reveal sodium changes in HD
A new brain scanning technique reveals high sodium levels in HD brains. How might this help clinical trials?
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Mapping the neighborhood: huntingtin's new protein partners
Study of huntingtin protein's 'neighbors' reveals dozens of new drug development targets
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Does the HD mutation affect children's growth?
A small study suggests kids with the HD mutation but no symptoms have subtle differences in growth. What does it mean
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'Induced' stem cells make exciting advances
Stem cells from HD patients: becoming important tools for researchers – and now correcting the HD mutation in the lab
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ASO gene silencing reaches further, lasts longer
Silencing the Huntingtin gene using ASO drugs reaches further, lasts longer and is safe. Human trial soon?
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Phosphodiesterase inhibitors: new HD drugs entering trials soon
CHDI and Pfizer announce exciting animal work and plans for a human trial with a drug targeting 'phosphodiesterases'.
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Interview: CHDI's scientific team
HDBuzz interviews the top scientists from CHDI, the largest funder of Huntington's disease research in the world.
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Exercise increases cellular recycling
Exercise boosts cellular recycling in mice. Could this be why exercise is also good for HD – or even help develop dru
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The HDBuzz Prize for young science writers
Announcing the HDBuzz Prize for young science writers!
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What's the connection between Huntington's Disease and cancer?
HD patients are less likely to get cancer, according to a study from Sweden – what does this mean?
HDBuzz Trial Tracker
Sites for Phase 3 trial for votoplam, INVEST-HD, now open. Updates on recruitment and first dosing imminent.
Progress update for NCT06585449 – A Study to Evaluate ALN-HTT02
Updates from the ongoing placebo-controlled Phase 2/3 FALCON-HD trial
Previously featured
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Cutting to the chase with CRISPR
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Artificial Intelligence enters the HD space as a diagnostic tool
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Blocking a toxic fragment: new mouse study highlights the importance of HTT1a in Huntington’s disease
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Between Care, Genes, and Systems: Navigating Huntington’s Disease as a Caregiver
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Your Wrist on Watch: Could a Smartwatch Reveal Huntington’s Disease Symptoms?
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