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AMT-130 at Four Years: Hopeful Signs, Complex Controls
12 min read
Latest News
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September 2026: This month in Huntington’s disease research
5 min read
September brought progress across the HD research landscape. From brain waves and visual thinking to DNA repeats, nutrition, inclusive care, new technologies, and encouraging SKY-0515 data, we round up a busy month in Huntington’s disease research.
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Through the eyes of a friend: changes in mood and behavior in early HD
8 min read
Companions of HD gene carriers are more likely to notice psychological changes in presymptomatic HD.
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A multiple sclerosis drug that works for Huntington's disease: the real deal or too good to be true?
8 min read
Fingolimod, a drug used in multiple sclerosis, prevents memory problems in HD mice. Would it work in patients?
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Mapping the anatomy of HD: a whole-brain history
10 min read
A new book for researchers describes a century of HD anatomy and presents evidence that HD affects the whole brain.
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Liftoff: First humans treated with gene silencing drugs for HD!
8 min read
Major Announcement: First HD patients treated with gene silencing drugs
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HDBuzz primer: Clinical trial designs and phases
17 min read
HDBuzz untangles hope from hype in clinical trial announcements
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A Few Bad Seeds: Using Brain Fluid to Grow Clumps in Brain Cells
7 min read
HD brain fluid makes brain cells grow clumps.
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New tool to measure outcomes in Huntington’s Disease clinical trials
6 min read
A better tool for HD trials! New research shows innovative way to measure mutant Huntingtin outside the brain
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Huge study reveals new 'genetic modifiers' of Huntington's disease
8 min read
GeM-HD identifies the first solid leads in the hunt for genetic variations that affect Huntington's disease onset
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Would ewe believe it? GM1, sheep and Huntington's disease
8 min read
HD researchers and sheep farmers are collaborating on a brain fat called GM1, but a clinical trial is a long way off
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Switching it up: variety in the HD gene affects symptom onset
9 min read
Variety in the HD gene’s on switch affects when symptoms arise.
HDBuzz Trial Tracker
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Updates from the ongoing Phase 3 INVEST-HD trial of votoplam
Updates from the Phase 1b/2a REGEN4HD trial of neural stem cell therapy hNSC-01
Updates from the ongoing Phase 2/3 FALCON-HD trial of SKY-0515
