Latest News
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Sealing the gap: a case for slower, smarter DNA repair
⏱️ 7 min read | Your body assembles DNA like a team of workers who set and bond a pattern of tiles. A recent study shows that one special assistant might slow somatic CAG expansion and delaying HD onset.
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Huntington's Disease Therapeutics Conference 2016 – day 3
Stem cells and modeling Huntington's disease in our final Therapeutics Conference report
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Huntington's Disease Therapeutics Conference 2016 – day 2
Strategies for getting rid of mutant huntingtin & clinical trial updates: day 2 of the HD therapeutics conference
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Huntington's Disease Therapeutics Conference 2016 – day 1
Proteins and DNA – Jeff and Ed report from day 1 of the 2016 #huntingtonsdisease therapeutics conference
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Harnessing the power of viruses to treat Huntington's disease
Researchers design a virus to more effectively deliver gene-silencing drugs throughout the brain.
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Through a Broader Lens: Looking at Non-Motor Symptoms in HD
Sleep deficits precede motor problems in HD
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Looking Past the Spin: Results from a Clinical Trial of Cysteamine
Phase 2/3 clinical trial results prove inconclusive for Huntington's drug cysteamine.
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A recycled drug gives us new insight in to HD
An existing drug could give a boost to HD brain cells – but it may need more testing before it’s back in the clinic
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Through the eyes of a friend: changes in mood and behavior in early HD
Companions of HD gene carriers are more likely to notice psychological changes in presymptomatic HD.
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A multiple sclerosis drug that works for Huntington's disease: the real deal or too good to be true?
Fingolimod, a drug used in multiple sclerosis, prevents memory problems in HD mice. Would it work in patients?
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Mapping the anatomy of HD: a whole-brain history
A new book for researchers describes a century of HD anatomy and presents evidence that HD affects the whole brain.
HDBuzz Trial Tracker
Sites for Phase 3 trial for votoplam, INVEST-HD, now open. Updates on recruitment and first dosing imminent.
REGEN4HD, Phase 1 stem cell implantation study commences
Progress update for NCT06585449 – A Study to Evaluate ALN-HTT02
Updates from the ongoing placebo-controlled Phase 2/3 FALCON-HD trial
Previously featured
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Sealing the gap: a case for slower, smarter DNA repair
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HDBuzz 2025 Annual Report: Here’s what you made possible
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Skyhawk reports encouraging 12-month results for oral Huntington’s disease drug SKY-0515
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May 2026: This Month in Huntington’s Disease Research
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Fixing the Recipe: Lowering a Slice of Huntingtin
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