HDBuzz – Page 27 – Huntington’s disease research news.

Huntington’s disease research news.

In plain language. Written by scientists.
For the global HD community.

Vaccines and Neurodegeneration: Lessons for Huntington’s Disease?

January 15, 2026

Latest News

UniQure Secures Type A Meeting with FDA: What This Means for AMT-130

⏱️6 min read | UniQure secured a Type A FDA meeting, a high-priority discussion for urgent issues. Within 30 days, both sides will discuss what kind of data package might support the advancement of AMT-130 in the US.

January 12, 2026

New study reveals a potential HD biomarker

A potential HD biomarker has been uncovered in a recent clinical study

June 7, 2017
Has a "wonder drug" for dementia been discovered? (Spoiler alert: no.)

Media reports of a wonder drug for neurodegenerative diseases like Huntington's disease are overhyped

May 7, 2017
Huntington's Disease Therapeutics Conference 2017 – Day 3

HDBuzz summarises final day of the 2017 Huntington's Disease Therapeutics Conference in Malta

April 30, 2017
Huntington's Disease Therapeutics Conference 2017 – Day 2

HDBuzz summarises all the science from the 2017 Huntington's Disease Therapeutics Conference in Malta – day 2

April 29, 2017
Huntington's Disease Therapeutics Conference 2017 – Day 1

HDBuzz summarises all the science from the 2017 Huntington's Disease Therapeutics Conference in Malta – day 1

April 27, 2017
Enemy at the gates – huntingtin disrupts nuclear transport

Two recent studies show how a cellular border control system goes wrong in HD, opening new avenues for HD research.

April 21, 2017
FDA approves a new drug for symptoms of Huntington's disease

Deutetrabenazine becomes the first new drug in a decade licensed by the FDA for symptoms of Huntington's disease

April 5, 2017
Sheep leading the flock: metabolism and biomarkers in HD

Sheep can help us to identify HD biomarkers and recognize metabolic changes that occur before symptoms develop.

March 27, 2017
Weeding out the truth: can cannabis improve Huntington’s?

What can individual experiences with cannabis tell us about Huntington's disease?

February 24, 2017
Huntingtin grabs a hammer: DNA repair in HD

Huntingtin helps fix damaged DNA, a recent study suggests, under the direction of a gene repair protein called ATM.

February 22, 2017

HDBuzz Trial Tracker

Type A Meeting FDA to Define Next Steps for AMT-130

uniQure

Expected: mid-Feb 2026

Topline data from SKY-0515’s Phase 1 Clinical Study

Skyhawk Therapeutics

Expected: Mid 2026

Phase 3 for SOM3355 to commence

SOM Biotech

Expected: Q4 2026

Progress update for NCT06585449 – A Study to Evaluate ALN-HTT02

Alnylam Pharmaceuticals

Expected: 2026

GENERATION-HD2 Trial Expected to Complete

Roche

Expected: 2026

Update on Planned Phase 2/3 Study for WVE-003

Wave Life Sciences

Expected: Not disclosed

Update on Phase 1/2a Clinical Data of VO659

Vico Therapeutics

Expected: Not disclosed

Additional insights from Phase 2 study results and update on plans for Phase 3 trial for votoplam

Novartis/PTC Therapeutics

Expected: Not disclosed

First participant in Phase 1/2 gene therapy trial dosed

Spark Therapeutics

Expected: Not disclosed

Previously featured

UniQure Secures Type A Meeting with FDA: What This Means for AMT-130

January 12, 2026
Putting Huntington’s disease medications to the test: results from the Neuro-HD trial

January 8, 2026
HDBuzz Is Officially Independent: What This Means, and Why It Matters

January 5, 2026
2025: Year in Review

December 29, 2025
Break Up With Your CAGs: How Three Letters Could Change Huntington’s Disease

December 22, 2025

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