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October 2025: This Month in Huntington’s Disease Research
Latest News
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Kids sometimes get Huntington’s disease too
Finally, a big study that shows what childhood HD looks like. This will help us work out if new drugs work in children too
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Roche announces details of its 'pivotal' huntingtin-lowering study
The GENERATION-HD1 trial will test whether RG6042 – formerly Ionis-HTTRx – slows the progression of Huntington's disease
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Disappointing news from LEGATO-HD trial of laquinimod in Huntington's disease
The LEGATO-HD trial of laquinimod did not slow progression of Huntington's disease. Here's the lowdown.
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HDBuzz Enrolls in Enroll-HD
As promised, HDBuzz's Jeff Carroll finally signed up for the Enroll-HD study. Learn more about this important global HD "observational study" here.
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First Dolly, now Piglet; a new Huntington’s disease pig knock-in model confirmed
For the first time in HD research, an animal model has been created in pigs using 2 cutting edge DNA editing t
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New collaboration seeks to speed Huntington's disease drug licensing
Critical Path Institute launches new initiative to get HD drugs licensed as quickly as possible
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HDSA’s Q&A on the latest huntingtin-lowering update from Ionis and Roche
Our friends at @hdsa have produced this really good Q&A document about the latest huntingtin-lowering news.
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Exciting Experiments in "Open Science" by Huntington's Researchers
Brave scientists open their notebooks to help drive HD research at the risk of getting "scooped".
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The structure of the protein that causes Huntington's disease, revealed
Huntingtin protein's structure is now clear thanks to cryo-electron microscopy. This is kind of a big deal
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Huntington's disease therapeutics conference 2018 – day 3
Updates from day 3 of the Huntington’s Disease Therapeutics Conference: huntingtin protein – and lowering it