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Mind Your Mouth: Huntington’s Disease and Oral Health
Latest News
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DNA Repair in Huntington’s Disease: Not Up to Par?
Genetic mutations occur everyday in our cells, but the vast majority of them are repaired. New research finds DNA repair is not on PAR in HD cells, causing mutations to build up in people with HD.
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The structure of the protein that causes Huntington's disease, revealed
Huntingtin protein's structure is now clear thanks to cryo-electron microscopy. This is kind of a big deal
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Huntington's disease therapeutics conference 2018 – day 3
Updates from day 3 of the Huntington’s Disease Therapeutics Conference: huntingtin protein – and lowering it
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Huntington's disease therapeutics conference 2018 – day 2
DNA takes centre stage for day 2 of the Huntington's Disease Therapeutics Conference in Palm Springs
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Huntington's disease therapeutics conference 2018 – day 1
Our daily roundup of the science presented at the 2018 HD Therapeutics Conference in Palm Springs
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An early role for the Huntington's disease gene – but don't believe all the headlines
A surprising new paper sheds light on the role of the HD gene early in development. Should we worry?
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New interest in an old target
Promising results in mice provide renewed optimism for mGluR5 antagonists
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Ask the expert: Q&A on the huntingtin-lowering trial program
In a Q&A coordinated by the UK HD Association, Dr Ed Wild answers questions on the recently-announced trial
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Success! ASO drug reduces levels of mutant protein in Huntington's disease patients
Amazing news from Ionis and Roche! HTTRx drug successfully lowers harmful huntingtin protein in spinal fluid
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Switch off the genome editor when you’re done
CRISPR genome editing just got an off-switch. We cut through the hype to explore the technology in HD
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A new way of thinking about trials to prevent Huntington's disease
Can we test drugs to delay or prevent the onset of Huntington's disease? New research suggests it's possible