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May 2025: This Month in Huntingtonās Disease Research
Latest News
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HD and Histamines: Targeting Hybrid Receptors to Quiet Stressful Brain Talk
Scientists recently used an antihistamine to quiet dopamine messages in the brain and treat HD-like symptoms in mice. But beware the hype suggesting that allergy medicines could be used to slow down HD.
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Changing jobs: converting other cell types into neurons
Because HD causes a loss of neurons in the brain, some researchers are exploring ways to replace them. Working with HD mice, scientists recently showed that supportive brain cells called glia can be coaxed into becoming new neurons.
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HD Young Adult Study defines the sweet spot: symptom-free with measurable changes
We know that HD-related changes can occur many years before symptom onset, but how early do those changes begin? A team of researchers set out to determine that with a new comprehensive study in pre-manifest HD young adults.
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Fountain of youth: HTT protein repairs neurons by maintaining youthful state
Another clue about the normal function of the huntingtin protein; a team of scientists has recently found that huntingtin seems to play an important role in repairing damaged nerve cells
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What does COVID-19 mean for Huntingtonās disease families and HD research?
COVID-19 update: what does it mean for HD families, how does it impact HD research, and how has it changed the way science works?
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New molecule can reverse the Huntington's disease mutation in lab models
A collaborative team of scientists from Canada and Japan have identified a small molecule which can change the CAG-repeat length in different lab models of Huntington's disease. #HuntingtonsDisease #DrugDiscovery
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Huntingtonās disease therapeutics conference 2020 – Day 3
HDBuzz reports from the annual Huntingtonās disease therapeutics conference in Palm Springs
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Huntingtonās disease therapeutics conference 2020 – Day 2
HDBuzz reports from the annual Huntingtonās disease therapeutics conference in Palm Springs
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Huntingtonās disease therapeutics conference 2020 – Day 1
HDBuzz reports from the annual Huntingtonās disease therapeutics conference in Palm Springs
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Screening the entire genome for new drug targets for HD
Scientists screen the ENTIRE genome to find new potential therapeutic targets for HD. This ambitious study provides a wealth of data for HD researchers