HDBuzz 2025 Annual Report: Here’s what you made possible
ā±ļø7 min read | In 2025, you helped us reach 329,000 people with independent, unbiased HD research news. Our 2025 Annual Report is here. Take a look at what we built together, and consider helping us keep going.
Last year, 329,000 people visited HDBuzz.
They came after a clinical trial result they didn’t understand. After a conversation with a doctor that left them with more questions than answers. After a late-night search trying to make sense of a regulatory decision that could affect someone they love. They came, as Huntingtonās disease (HD) families have been coming to HDBuzz for over a decade, because they needed someone to translate the science into plain language, without an agenda.
That’s what we do. And in 2025, we did more of it than ever before.
We’re in the final two weeks of our Fund the Buzz spring fundraising campaign, and we wanted to take a moment to show you exactly what your support has built ā and what we’re working toward next.
2025 was the biggest year in HDBuzz history
In 2025, HDBuzz published 100 articles, double our output from the year before and more than triple our historical average. This increase in articles reflects how the field of HD research and clinical trials is accelerating forward, with more discoveries, breakthroughs, and more companies than ever working to develop drugs for HD.
If you’re a regular reader, you may have noticed that we’ve moved to a twice-weekly publication schedule (usually Mondays and Thursdays), covering everything from HTT-lowering clinical trials to CRISPR delivery systems to the AMT-130 regulatory saga that had so many families anxious and searching for clarity.
Those 100 articles generated more than 630,000 page views. Our email list grew to nearly 5,000 subscribers, with an open rate above 40%, more than double the industry average for nonprofits. When news broke, people came. When results were confusing, they came. When things were disappointing, they came here to understand why.
A big part of what we think makes HDBuzz special is that every article we publish is written by scientists who understand the biology deeply enough to know what matters and what doesn’t, and who care enough about the HD community to explain it clearly. When a company puts out a press release, we cut through the spin to get to the actual science – what the data really show, what the limitations are, and what it means for families living with HD today. We don’t accept pharmaceutical funding. We don’t run ads. We don’t put anything behind a paywall. That independence is the whole point, and it’s only possible because readers like you choose to support us.
We invested in the next generation of HD science communicators
2025 wasn’t just about output. It was about sustainability.
We continued the HDBuzz Prize for Young Science Writers, sponsored by the Huntington’s Disease Foundation this year, training early-career researchers (PhD students, postdocs, and clinicians) to write accessibly for the HD community. Six prize winners contributed articles on topics ranging from EEG biomarkers in pre-symptomatic HD to the risks of lowering “good” HTT during therapeutic development. These are tomorrow’s leading HD scientists, learning today how to talk to the people their work is meant to help most.
We also partnered with the Huntington’s Disease Foundation and their inaugural HD-CAG (Career Advancement Grant) fellows, providing science communication mentorship to five outstanding postdoctoral researchers on the path to independence. Their work appeared on HDBuzz, reaching tens of thousands of readers.
Investing in the next generation of HD communicators is how HDBuzz stays strong for the long haul and ensures that future HD research superstars are trained to translate scientific findings directly with the HD community.
2025 highlights at a glance
- 100 articles published, double 2024, more than triple our historical average
- 329,000 unique visitors, 630,000+ page views
- ~5000 email subscribers, >40% open rate
- 6 HDBuzz Prize winners, 5 HD-CAG fellows mentored
- Brought HDBuzz into the black and built a reserve fund to ensure sustainability
- Zero pharmaceutical funding – ever
We showed up when it was hard
2025 brought some genuinely difficult news for the HD community. The AMT-130 regulatory developments were confusing, emotionally charged, and scientifically complex. When that story unfolded, HDBuzz was there, not to spin it, not to catastrophize, but to explain what happened, what it means, and what comes next.
That’s what independent science journalism allows for. And it’s especially important for the HD community so they have an educated, unbiased understanding of what the science means for them and their families.
What 2026 looks like
We officially became an independent 501(c)(3) nonprofit on January 1, 2026 – hoorah! That means stronger governance, greater donor confidence, and a more sustainable foundation for everything we do.
We are maintaining our twice-weekly publication schedule. We’re expanding mentorship programs and formalizing science communication training. We’re growing our global author network. We’re growing our editorial infrastructure, including the addition of an editorial manager, that will let leadership focus on strategy while keeping publication quality high. We’re also beginning to pursue additional funding streams and building the recurring donor base that will make HDBuzz financially sustainable for years to come.
2025 proved that this model works. The question for 2026 is whether we can grow it to match the pace of HD research and the community’s need for clear, independent interpretation of it.
Two weeks left to contribute to our spring campaign
The Fund the Buzz campaign runs through June 15, and this is the moment where individual decisions add up to something that matters.
If you read HDBuzz regularly, please consider giving. If a HDBuzz article helped you prepare for a clinic appointment, understand a trial result, or feel less alone in this disease, please consider giving. If you believe that HD families deserve access to accurate, unbiased science journalism with no strings attached, please consider giving.
Donate to HDBuzz
There’s no minimum. There’s no complicated form. There’s just a community of people who care about the same thing, choosing to keep it alive together.
Thank you for reading. Thank you for trusting us. And thank you for being part of what made 2025 possible.
Want the full picture?
We believe in transparency – of science, of our editorial process, and how we run this organization. Our full HDBuzz 2025 Annual Report is available below. It covers everything: content output, readership data, mentorship programs, financials, governance, and where we’re headed in 2026 and beyond.
From here out, we’ll be publishing an annual report each year that will live on our website, because we think the HD community deserves to know exactly how HDBuzz operates, where the money goes, and what we’re working toward.
You don’t have to read it to donate. But if you’re the kind of person who wants to know exactly what you’re supporting, we think you’ll like what you find.
Summary
- HDBuzz published 100 articles in 2025, double 2024 and more than triple our historical average
- 329,000 unique visitors and 630,000+ page views made 2025 our biggest readership year ever
- We mentored six young science writers through the HDBuzz Prize and five HD-CAG fellows through our HDF partnership
- We became an independent 501(c)(3) nonprofit on January 1, 2026
- We never accept pharmaceutical funding; HDBuzz is supported entirely by the HD community
- Fund the Buzz runs through June 15 – if HDBuzz has ever helped you, please consider giving
For more information about our disclosure policy see our FAQ…
