Huntington’s disease research news. In plain language. Written by scientists. For the global HD community.
Our second daily report from CHDI’s annual HD therapies meeting in Palm Springs, devoted to problems with energy generation and chemical pathways … and ways we might be able to fix them
In the first of our daily reports from CHDI’s annual HD therapies meeting in Palm Springs, we report on strategies to turn off the harmful gene and get brain cells communicating more effectively.
The connection between cellular energy levels and HD is more complicated than we previously thought, but in a way that opens a door to more possible treatments. It seems drugs that actually slow down the production of energy can rescue cells with the HD mutation from dysfunction and death.
Over the last few years, CHDI Inc. has become the largest single driving force behind the development HD treatments. CHDI’s annual therapeutics conference in Palm Springs, California, brings together pharmaceutical companies, biotechnology companies and researchers to share their latest, hottest findings and talk about the path to a cure. HDBuzz will be reporting from the conference – and we want your questions!
HDBuzz is now live! Your source for Huntington’s disease research news, in plain language, written by scientists, for the global HD community. Reliable, impartial and free to share, HDBuzz will bring you solid reasons to have hope, by explaining latest news from the worldwide effort to find effective treatments for HD.
A drug used to treat the symptoms of Alzheimer’s disease might be beneficial in HD through altering the balance of good and bad messages coming into neurons. New research in HD mice suggests that low doses of memantine might be best, and hopefully a planned trial of low-dose memantine in HD patients will give us the answer.
We all know that exercise and staying active are good for everyone, whether or not they are at risk of developing HD. A new study of lifestyle activities in people with the HD mutation suggests that staying active is even more important in HD, and that passive habits – especially during the teenage years – might be one factor that can cause earlier onset of HD symptoms.
The first in a monthly series of FAQ articles covering hot topics and burning issues in the science behind HD.
The search for better treatments for HD requires a lot of effort by researchers across the globe. Time is of the essence: the ideal time for a treatment for HD is yesterday. Scientific findings need to be made available sooner rather than later, so that others can build on what is already known. PLoS Currents HD is a new journal launched to speed up the process of scientific discovery in HD.