Huntington’s disease research news. In plain language. Written by scientists. For the global HD community.

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Interview: CHDI Management

Interview: CHDI Management

Dr Jeff Carroll on February 25, 2011

CHDI Foundation, Inc. is a unique drug discovery organization focused exclusively on rapidly developing therapies that slow the progression of HD. It is the biggest funder and organizer of HD research worldwide, but many people affected by HD have never heard of it. During CHDI’s Annual Therapeutics Conference in Palm Springs, HDBuzz spoke exclusively to three of its scientific leaders.

CHDI Report: Day 3

CHDI Report: Day 3

Dr Jeff Carroll on February 10, 2011

Our third and final daily report from CHDI’s annual HD therapies meeting in Palm Springs, covering chemicals that can help neurons to survive, and insights into CHDI’s most advanced experimental drug programs.

CHDI Report: Day 2

CHDI Report: Day 2

Dr Ed Wild on February 09, 2011

Our second daily report from CHDI’s annual HD therapies meeting in Palm Springs, devoted to problems with energy generation and chemical pathways … and ways we might be able to fix them

CHDI Report: Day 1

CHDI Report: Day 1

Dr Jeff Carroll on February 08, 2011

In the first of our daily reports from CHDI’s annual HD therapies meeting in Palm Springs, we report on strategies to turn off the harmful gene and get brain cells communicating more effectively.

Anti-nausea drug helps cells with the HD mutation stay healthy in a surprising way

Anti-nausea drug helps cells with the HD mutation stay healthy in a surprising way

Dr Jeff Carroll on February 04, 2011

The connection between cellular energy levels and HD is more complicated than we previously thought, but in a way that opens a door to more possible treatments. It seems drugs that actually slow down the production of energy can rescue cells with the HD mutation from dysfunction and death.

HDBuzz takes your questions to the annual therapeutics meeting of CHDI

HDBuzz takes your questions to the annual therapeutics meeting of CHDI

Dr Ed Wild on January 28, 2011

Over the last few years, CHDI Inc. has become the largest single driving force behind the development HD treatments. CHDI’s annual therapeutics conference in Palm Springs, California, brings together pharmaceutical companies, biotechnology companies and researchers to share their latest, hottest findings and talk about the path to a cure. HDBuzz will be reporting from the conference – and we want your questions!

Welcome to HDBuzz

Welcome to HDBuzz

Dr Ed Wild on January 18, 2011

HDBuzz is now live! Your source for Huntington’s disease research news, in plain language, written by scientists, for the global HD community. Reliable, impartial and free to share, HDBuzz will bring you solid reasons to have hope, by explaining latest news from the worldwide effort to find effective treatments for HD.

Memantine in HD: dose is everything

Memantine in HD: dose is everything

Dr Jeff Carroll on January 15, 2011

A drug used to treat the symptoms of Alzheimer’s disease might be beneficial in HD through altering the balance of good and bad messages coming into neurons. New research in HD mice suggests that low doses of memantine might be best, and hopefully a planned trial of low-dose memantine in HD patients will give us the answer.

An active lifestyle may make a difference to HD symptoms

An active lifestyle may make a difference to HD symptoms

Deepti Babu on January 10, 2011

We all know that exercise and staying active are good for everyone, whether or not they are at risk of developing HD. A new study of lifestyle activities in people with the HD mutation suggests that staying active is even more important in HD, and that passive habits – especially during the teenage years – might be one factor that can cause earlier onset of HD symptoms.