Gene silencing drug safe in ALS patients... bring on Huntington's disease trials

Gene silencing drug safe in ALS patients... bring on Huntington's disease trials

Gene silencing drug injected into spinal fluid in ALS patients proves safe. Good news for similar planned HD trials.

Joseph Ochaba | June 29, 2013

A DNA repair protein modifies the stability of long CAG tracts in the Huntington's disease gene

A DNA repair protein modifies the stability of long CAG tracts in the Huntington's disease gene

DNA repair is a critical process to cells, but errors in this process might explain 'repeat instability' in HD

Carly Desmond | June 03, 2013

Landmark study puts Huntington's disease trials on TRACK

Landmark study puts Huntington's disease trials on TRACK

Final results from the TRACK-HD study show very specific changes in HD. We're ready for trials: bring on the drugs!

Dr Faye Begeti | May 09, 2013

Splicing with danger: a new way of thinking about the harmful Huntington's disease protein

Splicing with danger: a new way of thinking about the harmful Huntington's disease protein

Researchers discover a new way harmful fragments of the huntingtin protein are made in neurons.

Dr Tamara Maiuri | May 06, 2013

Proposed Huntington's disease 'biomarker' is not useful, new study suggests

Proposed Huntington's disease 'biomarker' is not useful, new study suggests

New study shows a blood chemical called '8OHdG' is not a good biomarker for HD. Bad news?

Dr Jeff Carroll | April 25, 2013

Is access to predictive genetic testing for Huntington's disease a problem?

Is access to predictive genetic testing for Huntington's disease a problem?

Is access to predictive genetic testing for Huntington's disease a problem? A UBC study says it is.

Deepti Babu | April 23, 2013

HD Therapeutics Conference 2013 Updates: Day 3

HD Therapeutics Conference 2013 Updates: Day 3

Final day of our coverage of the Huntington's Disease Therapeutics Conference 2013

Dr Jeff Carroll | April 11, 2013

HD Therapeutics Conference 2013 Updates: Day 2

HD Therapeutics Conference 2013 Updates: Day 2

Day 2 of our coverage of the Huntington's Disease Therapeutics Conference

Professor Ed Wild | April 10, 2013

Major Roche-Isis deal boosts Huntington's disease gene silencing

Major Roche-Isis deal boosts Huntington's disease gene silencing

'ASO' gene silencing drugs for HD boosted by major deal between Isis Pharmaceuticals and Roche

Professor Ed Wild | April 09, 2013

HD Therapeutics Conference 2013 Updates: Day 1

HD Therapeutics Conference 2013 Updates: Day 1

Day 1 of our coverage of the Huntington's Disease Therapeutics Conference

Dr Jeff Carroll | April 09, 2013

Lost in translation? New insights into the making of the Huntington's disease protein

Lost in translation? New insights into the making of the Huntington's disease protein

Production of normal-length & extra-long huntingtin is controlled differently. A new way to keep cells healthy in HD?

Melissa Christianson | April 01, 2013

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