Latest news

HD and Histamines: Targeting Hybrid Receptors to Quiet Stressful Brain Talk

HD and Histamines: Targeting Hybrid Receptors to Quiet Stressful Brain Talk

Scientists recently used an antihistamine to quiet dopamine messages in the brain and treat HD-like symptoms in mice. But beware the hype suggesting that allergy medicines could be used to slow down HD.

Dr Leora FoxJuly 15, 2020

Changing jobs: converting other cell types into neurons

Changing jobs: converting other cell types into neurons

Because HD causes a loss of neurons in the brain, some researchers are exploring ways to replace them. Working with HD mice, scientists recently showed that supportive brain cells called glia can be coaxed into becoming new neurons.

Dr Sarah HernandezJune 23, 2020

HD Young Adult Study defines the sweet spot: symptom-free with measurable changes

HD Young Adult Study defines the sweet spot: symptom-free with measurable changes

We know that HD-related changes can occur many years before symptom onset, but how early do those changes begin? A team of researchers set out to determine that with a new comprehensive study in pre-manifest HD young adults.

Dr Sarah HernandezMay 27, 2020

Fountain of youth: HTT protein repairs neurons by maintaining youthful state

Fountain of youth: HTT protein repairs neurons by maintaining youthful state

Another clue about the normal function of the huntingtin protein; a team of scientists has recently found that huntingtin seems to play an important role in repairing damaged nerve cells

Dr Rachel Harding and Dr Sarah HernandezMay 13, 2020

What does COVID-19 mean for Huntington’s disease families and HD research?

What does COVID-19 mean for Huntington’s disease families and HD research?

COVID-19 update: what does it mean for HD families, how does it impact HD research, and how has it changed the way science works?

Dr Sarah Hernandez and Dr Ed WildApril 06, 2020

New molecule can reverse the Huntington's disease mutation in lab models

New molecule can reverse the Huntington's disease mutation in lab models

A collaborative team of scientists from Canada and Japan have identified a small molecule which can change the CAG-repeat length in different lab models of Huntington's disease. #HuntingtonsDisease #DrugDiscovery

Dr Michael FlowerApril 06, 2020

Huntington’s disease therapeutics conference 2020 - Day 1

Huntington’s disease therapeutics conference 2020 - Day 1

HDBuzz reports from the annual Huntington’s disease therapeutics conference in Palm Springs

Dr Rachel Harding, Dr Sarah Hernandez, and Joel StantonMarch 12, 2020

Huntington’s disease therapeutics conference 2020 - Day 3

Huntington’s disease therapeutics conference 2020 - Day 3

HDBuzz reports from the annual Huntington’s disease therapeutics conference in Palm Springs

Dr Sarah Hernandez, Dr Rachel Harding, and Joel StantonMarch 03, 2020

Huntington’s disease therapeutics conference 2020 - Day 2

Huntington’s disease therapeutics conference 2020 - Day 2

HDBuzz reports from the annual Huntington’s disease therapeutics conference in Palm Springs

Dr Rachel Harding, Dr Sarah Hernandez, and Joel StantonMarch 01, 2020

Screening the entire genome for new drug targets for HD

Screening the entire genome for new drug targets for HD

Scientists screen the ENTIRE genome to find new potential therapeutic targets for HD. This ambitious study provides a wealth of data for HD researchers

Dr Rachel HardingFebruary 23, 2020

The third dimension: using minibrains to understand brain development changes in HD

The third dimension: using minibrains to understand brain development changes in HD

Researchers show that highly expanded CAGs in the HD gene can cause early developmental changes using 3D brain models called organoids. What’d they find?

Dr Sarah HernandezFebruary 06, 2020