mouse-model
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Mapping the neighborhood: huntingtin's new protein partners
Study of huntingtin protein's 'neighbors' reveals dozens of new drug development targets
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Special 'brain fat' injection helps HD mice
Directly injecting the brains of HD mice with a good type of fat called ganglioside GM1 provides dramatic benefit
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Turning down the volume with dantrolene helps HD mice
Dantrolene, an muscle-relaxer drug already on the market, helps HD mice by reducing cellular calcium levels
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Gene silencing takes a targeted step forward
Targeting the mutant Huntington's disease gene for silencing, while leaving the healthy gene untouched