human
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The third dimension: using minibrains to understand brain development changes in HD
10 min read
Researchers show that highly expanded CAGs in the HD gene can cause early developmental changes using 3D brain models called organoids. What’d they find?
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HDSA FAQ on the Roche/Genentech RG6042 program
18 min read
HDSA's frequently asked questions factsheet about the huntingtin-lowering trial ASO program was so good we stole it (with permission)
By Dr Leora Fox -
Kids sometimes get Huntington’s disease too
6 min read
Finally, a big study that shows what childhood HD looks like. This will help us work out if new drugs work in children too
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HDBuzz Enrolls in Enroll-HD
12 min read
As promised, HDBuzz's Jeff Carroll finally signed up for the Enroll-HD study. Learn more about this important global HD "observational study" here.
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FDA approves a new drug for symptoms of Huntington's disease
4 min read
Deutetrabenazine becomes the first new drug in a decade licensed by the FDA for symptoms of Huntington's disease
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Sorry folks, the PRIDE-HD trial did NOT show that Pridopidine slows the progression of Huntington's disease
13 min read
HDBuzz helps untangle some bold claims about the just-announced results of the PRIDE-HD trial of pridopidine in HD
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Ultra-rare mutations highlight the importance of the HD gene in brain development
8 min read
New technology enables researchers to find ultra-rare mutations in the HD gene, distinct from the one causing HD
By Megan Krench -
Through a Broader Lens: Looking at Non-Motor Symptoms in HD
8 min read
Sleep deficits precede motor problems in HD
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Looking Past the Spin: Results from a Clinical Trial of Cysteamine
6 min read
Phase 2/3 clinical trial results prove inconclusive for Huntington's drug cysteamine.
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Through the eyes of a friend: changes in mood and behavior in early HD
8 min read
Companions of HD gene carriers are more likely to notice psychological changes in presymptomatic HD.
By Dr Leora Fox