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Could Brain Waves Help Track Huntington’s Disease?
⏱️7 min read | A review of 23 studies found that EEG changes were linked to disease progression and clinical measures in HD. While more research is needed, EEG holds potential to become a simple, non-invasive biomarker for monitoring HD over time.
By Dr Laura Ohl -
Keeping an Eye on HD: Can Visual Thinking Skills Help Track Disease Progression?
⏱️8 min read | What if Huntington’s disease changes how we “see” the world before we even notice symptoms? New research suggests visual thinking skills may help track HD progression over time.
By Eva Woods -
Putting it in print: a clinical trial trying to rein in runaway pruning
⏱️10 min read | Four years after announcing positive results in their trial of ANX005 (tanruprubart) for HD, Annexon has formally published the results. It’s safe, hits its target, and may have helped some participants – so what’s the holdup?
By Dr Leora Fox -
Mirror, Mirror on the Wall: When Self-Awareness Shifts in Huntington’s Disease
⏱️6 min read | A new study suggests that reduced awareness of symptoms, known as anosognosia, may appear even in the earliest stages of HD. The findings highlight that understanding symptom progression requires more than one perspective.
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More Than Just Food: The Hidden Challenges of Eating with Huntington’s Disease
⏱️8 min read | People with Huntington’s disease commonly experience unintended weight loss. A recent article identified the challenges around HD’s impact on eating and weight maintenance, and explored how families and professionals navigate them.
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Dancing With a Stranger: Understanding Apathy in Huntington’s Disease Through Caregivers
⏱️5 min read | Apathy in HD isn’t just “not caring.” It can affect relationships, routines, and emotional connection. A small study of caregivers reveals the heavy toll of apathy and the value of safe spaces to share experiences.
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Artificial Intelligence enters the HD space as a diagnostic tool
⏱️9 min read | From predicting symptom onset to tracking movement changes via smartwatch, artificial intelligence tools are being used in research. Here’s where we are, and why Huntington’s disease is a strong candidate for these approaches.
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UniQure and FDA No Longer in Alignment on Approval Pathway for AMT-130
In a new press release, uniQure shared that the FDA no longer agrees with their approach for advancing AMT-130, specifically the use of an external control group. The path forward is uncertain, but uniQure remains committed to the HD community.
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How Big Is The Huntington’s Disease Iceberg?
We can count how many people are seen in a clinic with Huntington’s disease by genetic testing, but how many people with the gene for HD are never diagnosed by a doctor? A new mathematical approach seeks to revisit this tricky question.
By Dr Chris Kay -
Body in Decline: Muscle Loss as an Early Symptom of Huntington’s Disease
Huntington’s disease doesn’t just damage the brain, it also breaks down muscles and fat, and disrupts nutrition early on. New work suggests there’s a hidden physical decline in early HD, so monitoring body changes could help with better care.