gene-silencing
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HDSA’s Q&A on the latest huntingtin-lowering update from Ionis and Roche
5 min read
Our friends at @hdsa have produced this really good Q&A document about the latest huntingtin-lowering news.
By Dr Leora Fox -
Huntington's disease therapeutics conference 2018 – day 3
14 min read
Updates from day 3 of the Huntington’s Disease Therapeutics Conference: huntingtin protein – and lowering it
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An early role for the Huntington's disease gene – but don't believe all the headlines
13 min read
A surprising new paper sheds light on the role of the HD gene early in development. Should we worry?
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Success! ASO drug reduces levels of mutant protein in Huntington's disease patients
11 min read
Amazing news from Ionis and Roche! HTTRx drug successfully lowers harmful huntingtin protein in spinal fluid
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New roles for huntingtin: removing a healthy protein to understand its function
7 min read
Completely removing normal huntingtin in adults may disrupt healthy brain function, a recent study suggests.
By Dr Leora Fox -
Precision huntingtin-lowering drug trials target the mutant protein
10 min read
WAVE Life Sciences launches PRECISION clinical trial to suppress the mutant Huntington's disease protein
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Update confirms Huntington's disease 'gene silencing' trial on track
10 min read
Ionis says its trial of HTTRx, intended to lower huntingtin protein, is fully recruited and plans to extend it
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Huntington's Disease Therapeutics Conference 2017 – Day 2
4 min read
HDBuzz summarises all the science from the 2017 Huntington's Disease Therapeutics Conference in Malta – day 2
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Important advances in next generation genome editing tools for Huntington's Disease
13 min read
Work with genome editing techniques (zinc fingers and CRISPR) brings these tools closer to use in HD clinical trials
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Planting trees together: The 2016 Huntington's Disease Society of America Convention
6 min read
HDBuzz summarizes the science from an unusually large and energized @HDSA convention in Baltimore