featured
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Bringing HD Treatments to Market: The Role of Regulatory Oversight
Moving drugs from the lab bench to pharmacy shelves is no small task. In this article we delve into the role regulatory oversight plays in clinical trials and the approval of medicines for Huntingtonās disease.
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Interruptions are encouraged
A CRISPR-based approach called ābase editingā is being explored to develop a new potential treatment for Huntington's disease. Editing a single letter in the genetic code with base editing may be the key for delaying HD symptoms, maybe by a decade.
By Dr Chris Kay -
HDBuzz needs your help
Weāre asking for your donation to ensure the continuity of our services. We want HDBuzz to be sustainable so that we can continue to report unbiased science to the HD community.
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14 changes for a healthier brain
In 2019, there were ~57 million people living with dementia. By 2050, that number is expected to climb to 153 million. Changes in the 14 factors highlighted here can improve brain health and be applied to Huntingtonās disease.
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Highlighting a link between brain disorders on Ataxia Awareness Day
September 25th is Ataxia Awareness Day, so HDBuzz is highlighting the connections between HD and Ataxia research. Learn about how these fields have historically grown in parallel and informed one another.
By Dr Leora Fox -
Hope vs. hype: seeking truth in recent Prilenia headlines
Although pridopidine has suffered four negative trials for HD, the message from Prilenia continues to be positive. What is hope and what is hype in this sixteen-year quest for regulatory approval?
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Mini brains grown in a dish shed light on Huntingtonās disease and how we might treat it
Exciting new findings using 3D human lab-grown mini brains inform ongoing HTT-lowering trials and suggest that stem cell transplants for HD may improve cell-to-cell communication and reduce disease features.
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Hereditary Disease Foundation (HDF) conference 2024 ā Day 4
Read our live tweet compilation from clinical trials and scientific research on Huntingtonās disease from Day 4 of the 2024 HDF Milton Wexler Biennial Symposium #HD2024
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Hereditary Disease Foundation (HDF) conference 2024 ā Day 3
Read our live tweet compilation from clinical trials and scientific research on Huntingtonās disease from Day 3 of the 2024 HDF Milton Wexler Biennial Symposium #HDF2024
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Hereditary Disease Foundation (HDF) conference 2024 ā Day 2
Read updates from clinical trials and scientific research on Huntingtonās disease from Day 2 of the 2024 HDF Milton Wexler Biennial Symposium #HDF2024