featured
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Knockouts for the win: how expanding CAGs drive disease
A recent paper links CAG repeat expansion with widespread RNA changes, especially in brain cells vulnerable to HD. âKnocking outâ certain DNA repair genes that go awry in HD can have positive effects on features of HD in mice.
By Dr Leora Fox -
Piecing It Back Together: Growing new neurons for Huntingtonâs disease
New research suggests the adult brain can be convinced to grow new neurons to replace those lost in Huntingtonâs disease. The SUPER exciting part? These cells donât just growâthey seem to connect and function, like puzzle pieces clicking into place.
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Stars in the Sky: Psychosis in Huntingtonâs Disease
New research shines a light on an often-overlooked side of Huntingtonâs diseaseâpsychosis. Understanding the impact of psychosis on daily life and progression of other HD symptoms could be key to providing better care and support.
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Hope in Full Bloom: Why Your Support Matters Now More Than Ever
Hope is in full bloom at HDBuzz! Weâre growingâdoubling article output, expanding our team, & keeping Huntingtonâs disease families informed. Now, we need YOUR help to stay independent & strong. Donate today & fuel free, trusted HD research news!
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March 2025: This Month in Huntingtonâs Disease Research
With so much science going on in the Huntingtonâs disease space, weâre bringing you a monthly recap from March 2025 to cover all the biggest HD science news and research we covered this month. Enjoy!
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Molecular Surgeons for Huntingtonâs Disease Catch a RIDE with CRISPR Advancements
A new CRISPR-based technology, called RIDE, is a leap forward for this trail-blazing technology. With the precision of a scalpel sharp enough to rewrite the very code of life, researchers have used it with the hope of treating Huntingtonâs disease.
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Huntingtonâs Disease Heroes: A Gratitude Day Feature on Factor-H
In honor of #HDGratitudeDay, happening today, March 23, 2025, HDBuzz interviewed Dr. Ignacio Muñoz-SanjuĂĄn, President and Founder of Factor-Hâa nonprofit dedicated to supporting Huntingtonâs disease families in Latin America.
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This Gratitude Day, HDBuzz Is Grateful For The Partnership Between HD Families And Scientists
This #HDGratitudeDay, weâre going beyond science & getting to the heart of what drives this communityâthe people. Learn how Factor-H is bringing hope & humanity to the most vulnerable within the HD community, and join us in amplifying their message.
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The Huntingtonâs Disease Youth Organizationâs World Congress: Supporting Young People Affected by HD
Young people impacted by Huntingtonâs disease donât have to face it alone. @HDYO provides support, education, and community to empower those up to age 35. Learn more about their mission and the recent HDYO International Young Adult Congress!
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Listening for Whispers: How a Tiny Protein Could Transform HD Research
A 14-year study tracking NfL levels in people with the HD gene shows this tiny protein can signal disease progression many years before symptoms start. The longest follow-up study yet adds weight to NfL as a powerful tool for HD research.