drug-development
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Has a "wonder drug" for dementia been discovered? (Spoiler alert: no.)
Media reports of a wonder drug for neurodegenerative diseases like Huntington's disease are overhyped
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FDA approves a new drug for symptoms of Huntington's disease
Deutetrabenazine becomes the first new drug in a decade licensed by the FDA for symptoms of Huntington's disease
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Important advances in next generation genome editing tools for Huntington's Disease
Work with genome editing techniques (zinc fingers and CRISPR) brings these tools closer to use in HD clinical trials
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Sorry folks, the PRIDE-HD trial did NOT show that Pridopidine slows the progression of Huntington's disease
HDBuzz helps untangle some bold claims about the just-announced results of the PRIDE-HD trial of pridopidine in HD
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Electron beam snaps best images yet of Huntington's disease protein
Electrons enable huntingtin protein, the cause of Huntington's disease, to be visualised at highest resolution ever
By Tom Peskett -
Huntingtin takes a trip: harmful proteins pass between brain cells
Harmful misfolded huntingtin can travel between brain cells via messenger particles called exosomes
By Dr Leora Fox -
How NOT to write a news article about a clinical trial
A confusing story about a huntingtin lowering trial is published in the Telegraph, but cool new stuff is happening!
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A recycled drug gives us new insight in to HD
An existing drug could give a boost to HD brain cells – but it may need more testing before it’s back in the clinic
By Dr Leora Fox -
Liftoff: First humans treated with gene silencing drugs for HD!
Major Announcement: First HD patients treated with gene silencing drugs
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New tool to measure outcomes in Huntington’s Disease clinical trials
A better tool for HD trials! New research shows innovative way to measure mutant Huntingtin outside the brain
By Megan Krench