drug-development
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What the 'big neurodegeneration breakthrough' means for Huntington's disease
10 min read
Are recent findings in mice injected with 'prions' as important for Huntington's disease as widely reported?
By Eric Minikel -
Targeting oxidative stress in Huntington's Disease
5 min read
Damage to cells caused by oxidative stress is part of HD – could a new targeted drug help reduce this problem?
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Shooting the messenger with single-stranded RNA gene silencing
7 min read
New ‘single-stranded RNA’ gene silencing drugs could be safer & more effective to treat Huntington’s disease
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Lithium with a twist gets second chance for HD
6 min read
Lithium gets a second chance in HD – with a new chemical delivery method, tested in Huntington’s disease mice
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Phosphodiesterase inhibitors: new HD drugs entering trials soon
6 min read
CHDI and Pfizer announce exciting animal work and plans for a human trial with a drug targeting 'phosphodiesterases'.
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'Floating' gene-silencing drugs into the brain with exosomes
6 min read
Exosomes – tiny bubbles made by cells – could be used to get gene silencing drugs from the bloodstream into the brain