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Could halting CAG expansions be a new treatment for HD?

Could halting CAG expansions be a new treatment for HD?

The gene MSH3 is getting a lot of attention in HD research lately. New findings suggest MSH3 lowering could halt CAG repeat expansions, offering a new therapeutic avenue.

Dr Sarah HernandezOctober 05, 2023

Are there genetic connections between neurodegenerative diseases?

Are there genetic connections between neurodegenerative diseases?

Genetic evidence suggests connections between a polyQ disease and ALS (Lou Gehrig’s disease). Why should HD people ca

Dr Jeff CarrollDecember 01, 2010

The genetic 'gray area' of Huntington's disease: what does it all mean?

The genetic 'gray area' of Huntington's disease: what does it all mean?

Intermediate alleles and reduced penetrance – the genetic 'gray area' of Huntington’s disease, explained

Dr Nayana LahiriApril 22, 2011

Gene therapy meets stem cells in liver disease success

Gene therapy meets stem cells in liver disease success

Scientists combine gene therapy and stem cells to correct a genetic liver disease. Could this combo be retooled for H

Dr Michael OrthDecember 26, 2011

Is a new technique set to revolutionize Huntington's disease genetic testing?

Is a new technique set to revolutionize Huntington's disease genetic testing?

A new genetic testing technique for HD has been reported. What does this mean for people at risk or already tested?

Dr Tamara MaiuriMarch 18, 2013

Is access to predictive genetic testing for Huntington's disease a problem?

Is access to predictive genetic testing for Huntington's disease a problem?

Is access to predictive genetic testing for Huntington's disease a problem? A UBC study says it is.

Deepti BabuApril 23, 2013

A DNA repair protein modifies the stability of long CAG tracts in the Huntington's disease gene

A DNA repair protein modifies the stability of long CAG tracts in the Huntington's disease gene

DNA repair is a critical process to cells, but errors in this process might explain 'repeat instability' in HD

Carly DesmondJune 03, 2013

What the 'big neurodegeneration breakthrough' means for Huntington's disease

What the 'big neurodegeneration breakthrough' means for Huntington's disease

Are recent findings in mice injected with 'prions' as important for Huntington's disease as widely reported?

Eric MinikelOctober 15, 2013

New study sheds light on regional degeneration in HD

New study sheds light on regional degeneration in HD

Why do certain brain cells die in HD? New research suggests is may be due to the efficiency of cellular recycling

Dr Kurt JensenNovember 12, 2013

Jumping genes: Huntington's disease protein invades brain transplants

Jumping genes: Huntington's disease protein invades brain transplants

A long-term study of the brains of HD patients who received grafts of fetal tissue reveals a surprising result

Dr Jeff CarrollMay 26, 2014

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