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Fresh Updates from First Huntingtin Lowering Study Publication
Hot off the presses - New publication gives more details about the results of Ionis and Roche's safety study with a Huntingtin-lowering ASO
May 07, 2019
Could molecular handcuffs lower the protein that causes Huntington's disease?
Researchers got surprisingly lucky when looking for drug molecules to pull mutant huntingtin protein into a cellular garbage disposal machine
November 12, 2019
Unpacking Wave's PRECISION-HD2 huntingtin-lowering trial announcement
Wave Life Sciences announces that its antisense drug WVE-120102 has lowered mutant huntingtin protein in cerebrospinal fluid, but investors seem disappointed. Rather confusing – what do we know for sure?
January 03, 2020
The third dimension: using minibrains to understand brain development changes in HD
Researchers show that highly expanded CAGs in the HD gene can cause early developmental changes using 3D brain models called organoids. What’d they find?
February 06, 2020
Screening the entire genome for new drug targets for HD
Scientists screen the ENTIRE genome to find new potential therapeutic targets for HD. This ambitious study provides a wealth of data for HD researchers
February 23, 2020
Huntington’s disease therapeutics conference 2020 - Day 2
HDBuzz reports from the annual Huntington’s disease therapeutics conference in Palm Springs
March 01, 2020
Huntington’s disease therapeutics conference 2020 - Day 3
HDBuzz reports from the annual Huntington’s disease therapeutics conference in Palm Springs
March 03, 2020
Huntington’s disease therapeutics conference 2020 - Day 1
HDBuzz reports from the annual Huntington’s disease therapeutics conference in Palm Springs
March 12, 2020
What does COVID-19 mean for Huntington’s disease families and HD research?
COVID-19 update: what does it mean for HD families, how does it impact HD research, and how has it changed the way science works?
April 06, 2020
New molecule can reverse the Huntington's disease mutation in lab models
A collaborative team of scientists from Canada and Japan have identified a small molecule which can change the CAG-repeat length in different lab models of Huntington's disease. #HuntingtonsDisease #DrugDiscovery
April 06, 2020
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