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Unlocking the Potential of Antibodies as a Therapy for Huntington’s Disease

Unlocking the Potential of Antibodies as a Therapy for Huntington’s Disease

Antibodies are known for their role in immunity, but researchers repurpose them in many ways. Can they be used in HD?

Lakshini MendisFebruary 18, 2015

2015 Huntington's Disease Therapeutics Conference: Day 1

2015 Huntington's Disease Therapeutics Conference: Day 1

Day 1 of updates from the annual HD Therapeutics Conference in Palm Springs

Professor Ed WildFebruary 25, 2015

Taking new targets to the bank: the DNA repair protein ‘ATM’ is overactive in Huntington's disease

Taking new targets to the bank: the DNA repair protein ‘ATM’ is overactive in Huntington's disease

HD causes the normally helpful protein "ATM" to get a little overzealous. Now we can look for drugs to settle it down

Terry Jo BichellMarch 09, 2015

Building a Better Mouse(trap): A New Model of Huntington’s Disease

Building a Better Mouse(trap): A New Model of Huntington’s Disease

New mouse model gives insights into Huntington's disease

Melissa ChristiansonMarch 16, 2015

A faulty filter? Blood vessel changes in Huntington's disease

A faulty filter? Blood vessel changes in Huntington's disease

New research reveals blood vessel changes that could contribute to problem in HD

Melissa ChristiansonMay 13, 2015

Would ewe believe it? GM1, sheep and Huntington's disease

Would ewe believe it? GM1, sheep and Huntington's disease

HD researchers and sheep farmers are collaborating on a brain fat called GM1, but a clinical trial is a long way off

Dr Leora FoxJuly 28, 2015

A Few Bad Seeds: Using Brain Fluid to Grow Clumps in Brain Cells

A Few Bad Seeds: Using Brain Fluid to Grow Clumps in Brain Cells

HD brain fluid makes brain cells grow clumps.

Melissa ChristiansonSeptember 15, 2015

HDBuzz primer: Clinical trial designs and phases

HDBuzz primer: Clinical trial designs and phases

HDBuzz untangles hope from hype in clinical trial announcements

Dr Jeff Carroll and Melissa ChristiansonOctober 09, 2015

Mapping the anatomy of HD: a whole-brain history

Mapping the anatomy of HD: a whole-brain history

A new book for researchers describes a century of HD anatomy and presents evidence that HD affects the whole brain.

Dr Leora FoxNovember 04, 2015

A multiple sclerosis drug that works for Huntington's disease: the real deal or too good to be true?

A multiple sclerosis drug that works for Huntington's disease: the real deal or too good to be true?

Fingolimod, a drug used in multiple sclerosis, prevents memory problems in HD mice. Would it work in patients?

Melissa ChristiansonNovember 24, 2015

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