Latest News
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ASO gene silencing reaches further, lasts longer
⏱️ 7 min read
Silencing the Huntingtin gene using ASO drugs reaches further, lasts longer and is safe. Human trial soon?
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Phosphodiesterase inhibitors: new HD drugs entering trials soon
⏱️ 6 min read
CHDI and Pfizer announce exciting animal work and plans for a human trial with a drug targeting 'phosphodiesterases'.
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Interview: CHDI's scientific team
⏱️ 8 min read
HDBuzz interviews the top scientists from CHDI, the largest funder of Huntington's disease research in the world.
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Exercise increases cellular recycling
⏱️ 5 min read
Exercise boosts cellular recycling in mice. Could this be why exercise is also good for HD – or even help develop dru
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The HDBuzz Prize for young science writers
⏱️ 3 min read
Announcing the HDBuzz Prize for young science writers!
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What's the connection between Huntington's Disease and cancer?
⏱️ 6 min read
HD patients are less likely to get cancer, according to a study from Sweden – what does this mean?
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Closing the care gap: new guidelines for HD care
⏱️ 6 min read
Closing the care gap: new guidelines to help every Huntington's disease patient get great care
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Stem-cell neurons make the right connections
⏱️ 7 min read
Replacing neurons in mice with stem cells works much better than expected, suggesting that replacement therapy might
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2012 Therapeutics Conference: a retrospective
⏱️ 19 min read
HDBuzz looks back at the 2012 Huntington's Disease Therapeutics Conference
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Mutant yeast highlights crucial CAG-reading protein
⏱️ 5 min read
A new job for a DNA-reading protein called SPT4 – controlling the balance of mutant and healthy huntingtin protein
HDBuzz Trial Tracker
Show 8 more Show less
Updates from the ongoing Phase 3 INVEST-HD trial of votoplam
Updates from the Phase 1b/2a REGEN4HD trial of neural stem cell therapy hNSC-01
Updates from the ongoing Phase 2/3 FALCON-HD trial of SKY-0515
Previously featured
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Turning down huntingtin: Alnylam’s brezosiran shows promising early result
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Picking MSH3’s Pocket: New Insights into CAG Repeat Expansion
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What Pigs Revealed that Mice Missed in Huntington’s Disease
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Mending the fabric of your genes
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Could rewiring the brain’s “brakes” improve movement in Huntington’s disease?
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